Lisa A Desjardins

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The effect of interleukin-1 beta, the major component of osteoclast-activating factor (OAF), on bone formation by fetal rat osteoblast-rich cells was investigated. An in vitro culture system developed by Ecarot-Charrier et al. (1983) and Bellows et al. (1986) was utilized in which osteoblasts form mineralized nodules which closely resemble woven bone.(More)
BACKGROUND The RAS/RAF/MEK/ERK pathway is involved in the balance between melanocyte proliferation and differentiation. The same pathway is constitutively activated in cutaneous and uveal melanoma (UM) and related to tumour growth and survival. Whereas mutant BRAF and NRAS are responsible for the activation of the RAS/RAF/MEK/ERK pathway in most cutaneous(More)
New collections of cestodes from the spiral intestines of catsharks (Carcharhiniformes: Scyliorhinidae) off Taiwan have led to the discovery of a new genus and 2 new species of trypanorhynchs. These taxa are relatively unique among trypanorhynchs in their lack of all elements of the rhyncheal apparatus. The new genus, Nakayacestus n. gen., is considered to(More)
New collections of cestodes from the spiral intestines of the lanternsharks Etmopterus spinax and Etmopterus pusillus off the island of Faial, in the Azores, Atlantic Ocean, have yielded 2 new species of trypanorhynchs belonging to Aporhynchus. Both species share the distinctive lack of all elements of the rhyncheal system that are characteristic of this(More)
Cancer survival has improved, and more attention is now being focused on quality of life. Quality-of-life issues include the physical, psychological, social, spiritual, and financial aspects of caring. Because patient support services can play an important role in helping patients cope with their disease, they are critical to patients with cancer and their(More)
Hepatocellular carcinoma (HCC) is a common malignancy worldwide and is a disease of multifactorial etiology. Strong correlations exist between the prevalence of the hepatitis B and C viruses and HCC incidence. HCC treatment may involve surgical resection, liver transplantation, locoregional treatments, and chemotherapy. Prevention of virus-related HCC is(More)
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