Liron Philosof-Mazor

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Synthetic diacylglycerol lactones (DAG-lactones) have been shown to be effective modulators of critical cellular signaling pathways. The biological activity of these amphiphilic molecules depends in part upon their lipid interactions within the cellular plasma membrane. This study explores the thermodynamic and structural features of DAG-lactone derivatives(More)
Bolaamphiphiles - amphiphilic molecules consisting of two hydrophilic headgroups linked by a hydrophobic chain - form highly stable vesicles consisting of a monolayer membrane that can be used as vehicles to deliver drugs across biological membranes, particularly the blood-brain barrier (BBB). We prepared new vesicles comprising bolaamphiphiles(More)
bottom-up approaches have emerged as promising alternatives for generation of organized nanostructures and electronic components. [ 4 ] Bottom-up techniques generally rely upon molecular self-assembly phenomena to produce defi ned structures that could be practically utilized. [ 5 , 6 ] Here, we describe a new bottom-up approach for construction of thin-fi(More)
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