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Genome-scale screening studies are gradually accumulating a wealth of data on the putative involvement of hundreds of genes in various cellular responses or functions. A fundamental challenge is to chart the molecular pathways that underlie these systems. ANAT is an interactive software tool, implemented as a Cytoscape plug-in, for elucidating functional(More)
With the unparalleled increase in the availability of biological data over the last couple of decades, accurate and computable models are becoming increasingly important for unraveling complex biological phenomena. Past efforts to model signaling networks have utilized various computational methods, including Boolean and constraint-based modeling (CBM)(More)
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