Liqun Zhao

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Oxidative DNA damage has been proposed to be a major contributor to focal cerebral ischemic injury. However, little is known about the role of oxidative DNA damage in remote damage secondary to the primary infarction. In the present study, we investigated oxidative damage within the ventroposterior nucleus (VPN) after distal middle cerebral artery occlusion(More)
Jingzhaotoxin-34 (JZTX-34) is a 35-residue polypeptide from the venom of Chinese tarantula Chilobrachys jingzhao. Our previous work reported its full-length cDNA sequence encoding a precursor with 87 residues. In this study we report the protein expression and biological function characterization. The toxin was efficiently expressed by the secretary pathway(More)
—There is a form of unfairness phenomenon found in data center networks,which was identified by P. Prakash. This phenomenon shows that the throughput of a flow with smaller RTT is less than the throughput of a flow with large RTT. This is completely contrary to the classic TCP protocol. P. Prakash gives an explanation based on port blackout theory. However,(More)
We even reported that hydrogen peroxide (H2O2) acts upstream of nitric oxide (NO) in the heat shock (HS) pathway in Arabidopsis (Arabidopsis thaliana) seedlings. In this work, we found a strange phenomenon that exogenous application of high concentration of H2O2 could not elevate internal H2O2 level under HS. NO donors sodium nitroprusside (SNP) and(More)
Cellular FLICE inhibitory protein (c-FLIP), a truncated form of caspase-8 that lacks caspase enzymatic activity, primarily acts as a specific inhibitor of the extrinsic death receptor-mediated apoptotic pathway [1]. Typically, a death ligand (e.g., TRAIL) binds to its corresponding death receptor (e.g., DR5) to induce oligomerization of the receptors. This(More)
Salt is a major threat to plant growth and crop productivity. Calmodulin (CaM), the most important multifunctional Ca2+ sensor protein in plants, mediates reactions against environmental stresses through target proteins; however, direct proof of the participation of CaM in salt tolerance and its corresponding signaling pathway in vivo is lacking. In this(More)
BACKGROUND Hybrid cells produced by fusions of tumor and dendritic cells (DC) have demonstrated remarkable efficacy for priming the anti-tumor immune response. In the current study, we examined the antitumor activity of cytotoxic T lymphocytes (CTLs) primed in response to a tumor vaccine comprising a glioma-DC fusion as part of a therapeutic against glioma.(More)
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