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A key question in sensory perception is the role of experience in shaping the functional architecture of the sensory neural systems. Here we studied dependence on visual experience in shaping the most fundamental division of labor in vision, namely between the ventral "what" and the dorsal "where and how" processing streams. We scanned 11 fully congenitally(More)
The visual word form area (VWFA) is a ventral stream visual area that develops expertise for visual reading. It is activated across writing systems and scripts and encodes letter strings irrespective of case, font, or location in the visual field with striking anatomical reproducibility across individuals. In the blind, comparable reading expertise can be(More)
PURPOSE To describe instances of inadvertent intrathecal injection of ionic contrast media and to consider treatment approaches, and diagnostic and medicolegal issues. METHODS Ten cases of inadvertent injection, of which nine were reported to the manufacturers/authors and one appeared in the literature, are related with emphasis on similarity of(More)
PURPOSE OF REVIEW The exciting view of our brain as highly flexible task-based and not sensory-based raises the chances for visual rehabilitation, long considered unachievable, given adequate training in teaching the brain how to see. Recent advances in rehabilitation approaches, both noninvasive, like sensory substitution devices (SSDs) which present(More)
We measured the activity of 2 highly specific autoantibodies (anti-Yo associated with paraneoplastic cerebellar degeneration and anti-Hu associated with paraneoplastic sensory neuronopathy-encephalomyelitis) in simultaneously procured samples of serum and CSF of 18 patients. We also measured the effect of plasma exchange on autoantibody activity in serum(More)
With an alpha-galactosidase, B erythrocytes can be converted to blood group O under conditions that neither impair their viability in vitro nor affect their ability to survive normally after transfusion to individuals of groups O, A, and B. Such an approach has the potential for producing enzymatically converted group O cells for use in transfusion therapy.(More)
Cases of invasive sight-restoration in congenital blind adults demonstrated that acquiring visual abilities is extremely challenging, presumably because visual-experience during critical-periods is crucial for learning visual-unique concepts (e.g. size constancy). Visual rehabilitation can also be achieved using sensory-substitution-devices (SSDs) which(More)
We have assessed the effect of the donation of autologous blood and the preoperative level of haemoglobin on the prevalence of postoperative thromboembolism in 2043 patients who had a total hip arthroplasty. The level of haemoglobin was determined seven to ten days before surgery and all patients had venography of the operated leg on the fifth postoperative(More)
Here we studied how congenitally blind subjects represent space in the brain and whether they have spatiotopic maps similar to the sighted. We asked 8 congenitally blind subjects to read specifically designed braille letters with a dot missing in either of the four corners of the braille grid (upper right, upper left, lower right and lower left) and to(More)
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