Linmei Wang

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Dimethyl sulfoxide (DMSO) is a polar organic solvent that is used to dissolve neuroprotective or neurotoxic agents in neuroscience research. However, DMSO itself also has pharmacological and pathological effects on the nervous system. Astrocytes play a central role in maintaining brain homeostasis, but the effect and mechanism of DMSO on astrocytes has not(More)
BACKGROUND Alzheimer's disease is a neurodegenerative disease characterized by gradual declines in social, cognitive, and emotional functions, leading to a loss of expected social behavior. Social isolation has been shown to have adverse effects on individual development and growth as well as health and aging. Previous experiments have shown that social(More)
The web contains a wealth of user reviews about a topic concerning positive, negative or mixed mood, but it is a daunting task to discriminate them manually. This paper presents an approach for automatic sentiment analysis by 1) generating positive and negative sentiment words from Tongyici Cilin with paradigm words, 2) determining the sentiment orientation(More)
Early social isolation (SI) produces a variety of emotional, behavioral and cognitive abnormalities. Conversely, environmental enrichment (EE), a complicated social and physical construct, offers beneficial effects on brain plasticity and development. However, whether or not exclusive physical EE is sufficient to reverse the adverse consequences of early SI(More)
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