Linling Ma

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With the rapid development of application of LBS (Location Based Service) model, "checkin" has become a hot word. Since the geographic position is combined with local business resources, users can interact with shops through mobile. This Mobile SNS conceals a great deal of valuable information, including users' consumption tendency, merchants' marketing(More)
Pyrroline-5-carboxylate reductase (P5CR), an enzyme with conserved housekeeping roles, is involved in the etiology of cutis laxa. While previous work has shown that the R119G point mutation in the P5CR protein is involved, the structural mechanism behind the pathology remains to be elucidated. In order to probe the role of the R119G mutation in cutis laxa,(More)
Pyrroline-5-carboxylate reductase (P5CR1) is a universal housekeeping enzyme that catalyzes the reduction of Δ1-pyrroline-5-carboxylate (P5C) to proline with concomitant oxidation of NAD(P)H to NAD(P)+. The enzymatic cycle between P5C and proline is important for function in amino acid metabolism, apoptosis, and intracellular redox potential balance in(More)
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