Linh Thi Thao Nguyen

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Molecules of keystone significance are relatively rare, yet mediate a variety of interactions between organisms. They influence the distribution and abundance of species, the transfer of energy across multiple trophic levels, and thus they play significant roles in structuring ecosystems. Despite their potential importance in facilitating our understanding(More)
Ondansetron was formulated into a transdermal matrix patch to reduce side effects and improve patient compliance. The effects of adhesive (polyisobutylene rubber, acrylic, and styrene butadiene rubber), crosslinker content (aluminum), vehicle (lactic acid), and drug amount on ondansetron skin permeation rate were investigated using excised hairless mouse(More)
The aggregation of α-synuclein (aSyn) leading to the formation of Lewy bodies is the defining pathological hallmark of Parkinson's disease (PD). Rare familial PD-associated mutations in aSyn render it aggregation-prone; however, PD patients carrying wild type (WT) aSyn also have aggregated aSyn in Lewy bodies. The mechanisms by which WT aSyn aggregates are(More)
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