Linh Nguyen

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The brief negative symptom scale: psychometric properties.

Brian R. Kirkpatrick, Gregory P. Strauss, +4 authors Stephen R. Marder
Schizophrenia bulletin
2011

The participants in the NIMH-MATRICS Consensus Development Conference on Negative Symptoms recommended that an instrument be developed that measured blunted affect, alogia, asociality, anhedonia, and… (More)

Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2.

Jonathan D. Oliner, Hosung Min, +40 authors Richard Kendall
Cancer cell
2004

Angiopoietin-2 (Ang2) exhibits broad expression in the remodeling vasculature of human tumors but very limited expression in normal tissues, making it an attractive candidate target for… (More)

Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours

Jérôme Galon, Bernhard Mlecnik, +45 authors Franck Pagès
The Journal of pathology
2014

The American Joint Committee on Cancer/Union Internationale Contre le Cancer (AJCC/UICC) TNM staging system provides the most reliable guidelines for the routine prognostication and treatment of… (More)

Bcl10 Is a Positive Regulator of Antigen Receptor–Induced Activation of NF-κ B and Neural Tube Closure

Juergen Ruland, Gordon S. Duncan, +8 authors Tak W Mak
Cell
2001

Bcl10, a CARD-containing protein identified from the t(1;14)(p22;q32) breakpoint in MALT lymphomas, has been shown to induce apoptosis and activate NF-kappaB in vitro. We show that one-third of… (More)

CD30 is a survival factor and a biomarker for transformed human pluripotent stem cells

Daniella Herszfeld, Ernst J Wolvetang, +14 authors Martin F Pera
Nature Biotechnology
2006

The application of human embryonic stem (hES) cells in regenerative medicine will require rigorous quality control measures to ensure the safety of hES cell–derived grafts. During propagation in… (More)

On reconstruction and time reversal in thermoacoustic tomography in acoustically homogeneous and inhomogeneous media

Yulia Hristova, Peter Kuchment, Linh Nguyen
2008

The paper starts with a comparative discussion of features and limitations of the three types of recent approaches to the reconstruction in thermoacoustic/photoacoustic tomography: backprojection… (More)

Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance.

Husein Hadeiba, Katharina Lahl, +7 authors Eugene C. Butcher
Immunity
2012

Central tolerance can be mediated by peripheral dendritic cells (DCs) that transport innocuous antigens (Ags) to the thymus for presentation to developing T cells, but the responsible DC subsets… (More)

Fluoride induces endoplasmic reticulum stress in ameloblasts responsible for dental enamel formation.

Kaori Kubota, Daniel Hong Seng Lee, +7 authors John Bartlett
The Journal of biological chemistry
2005

The mechanism of how fluoride causes fluorosis remains unknown. Exposure to fluoride can inhibit protein synthesis, and this may also occur by agents that cause endoplasmic reticulum (ER) stress.… (More)

The accuracy of probabilistic versus temporal clinician prediction of survival for patients with advanced cancer: a preliminary report.

David Hui, Kelly Kilgore, +17 authors Eduardo F Bruera
The oncologist
2011

Clinicians have limited accuracy in the prediction of patient survival. We assessed the accuracy of probabilistic clinician prediction of survival (CPS) and temporal CPS for advanced cancer patients… (More)

Pharmacokinetic (PK) drug interaction studies of cabozantinib: Effect of CYP3A inducer rifampin and inhibitor ketoconazole on cabozantinib plasma PK and effect of cabozantinib on CYP2C8 probe…

Linh Nguyen, Jaymes S Holland, +4 authors Steven A Lacy
Journal of clinical pharmacology
2015

Cabozantinib is a small-molecule tyrosine kinase inhibitor that has been approved for the treatment of patients with progressive, metastatic medullary thyroid cancer. In vitro data indicate that (1)… (More)

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