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In this paper, the method for the derivatization of carbohydrates with 1-phenyl-3-methyl-5-pyrazolone (PMP) was simplified. One-third of the derivatization time was saved. Five monosaccharide derivatives have been well separated by MEKC and HPLC under optimized conditions. Good reproducibility could be obtained with relative standard deviation (RSD) values(More)
The expression of alpha-fetoprotein (AFP), a tumor-associated antigen, is silenced in normal adult hepatocyte but reactivated in human hepatocellular carcinoma (HCC). To investigate the roles of AFP in the regulation of cell growth, we silenced AFP expression in the HCC cell line Huh7 by transfection of specific Stealth RNAi. After the transfection for 48(More)
This study was specifically designed to identify anticancer constituents in methanol-water extract of Polygonum bistorta L. and evaluate its cytotoxicity. For this purpose methanol-water (40:60 v/v) extract was subjected to conventional preparative high pressure liquid chromatography and 13 fractions were obtained. Constituents of obtained fractions were(More)
1-Bromopropane (1-BP), an alternative to ozone-depleting solvents, is reported to exhibit neurotoxicity and reproductive toxicity in animals and humans. However, the underlying mechanism of the toxicity remains elusive. This study was designed to identify the microglial changes and oxidative stress in the central nervous system (CNS) after 1-BP exposure.(More)
UNLABELLED Chronic hepatitis B (CHB) is major global health problem. In China, where about 120,000,000 persons are chronically infected, CHB has been treated for centuries with traditional Chinese medicines (TCMs). This review summarizes and meta-analyzes the results of randomized controlled trials (RCTs) of TCM formulations reported in China in 1998-2008(More)
The Internet today offers primarily a best-effort service. Research and technology development efforts are currently underway to allow provisioning of better than best-effort Quality of Service (QoS) assurances. In this article, we develop a spot pricing framework for intra-domain expected bandwidth contracts with loss based QoS guarantees. The framework(More)
OBJECTIVES To investigate the health effects of 1-bromopropane (1-BP) and its dose-dependency in 1-BP production factories in China. METHODS Data of 60 female and 26 male workers in three 1-BP factories and the same number of age-, sex-, and region-matched controls were interviewed and examined. The time-weighed average exposure levels of individual(More)
The Internet today offers primarily a best-effort service. Research and development efforts are currently underway to allow the provision of better than best-effort quality of service assurances. In this article we develop a spot-pricing framework for bandwidth assured Internet service contracts. A nonlinear pricing model forms the basis for the framework.(More)
Lupeol (Lup-20(29)-en-3H-ol), a novel dietary triterpene, was found in fruits, vegetables, and several medicinal plants. Here, we investigated its growth-inhibitory effect and associated mechanisms in hepatocellular carcinoma SMMC7721 cells. Lupeol treatment resulted in significant inhibition of cell viability in a dose-dependent manner and caused apoptotic(More)
The Internet today mostly offers a simple best-effort mode of service. The capabilities of the Internet will be significantly enhanced if it supports better QoS modes, especially when QoS is provided for end-to-end services. This enhancement in the Internet's capabilities requires both technological development and economic mechanisms to support better QoS(More)