Lingxiao Zhou

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A pharmacophore model consists of a group of chemical features arranged in three-dimensional space that can be used to represent the biological activities of the described molecules. Clustering of molecular interactions of ligands on the basis of their pharmacophore similarity provides an approach for investigating how diverse ligands can bind to a specific(More)
PURPOSE To determine the clinical features of traumatic ciliochoroidal detachment (CCD), and to evaluate the surgical outcomes. METHODS We retrospectively reviewed the records of 37 consecutive patients with traumatic CCD who underwent surgical procedures, including ciliary body suturing, transscleral cyclophotocoagulation, and cyclocryopexy. A complete(More)
PURPOSE To investigate postoperative inhibition of cell proliferation in animals treated with exogenous p27Kip1 during an experimental glaucoma filtration surgery (GFS) by histological and ultrastructural examinations. METHODS The primer was designed according to p27Kip1 gene sequence of GenBank. The p27Kip1-expressing adenovirus-mediated Ad-p27 was(More)
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