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The role of vitamin D in ovarian cancer: epidemiology, molecular mechanism and prevention
Vitamin D is a fat-soluble prohormone best known for its role in maintaining calcium homeostasis. Large numbers of epidemiological studies have shown that vitamin D plays an important role in cancer… Expand
Glutaminase inhibitor compound 968 inhibits cell proliferation and sensitizes paclitaxel in ovarian cancer.
- Lingqin Yuan, X. Sheng, +7 authors V. Bae-Jump
- Chemistry, Medicine
- American journal of translational research
OBJECTIVE Our overall goal was to investigate the anti-tumor activity of the glutaminase 1 (GLS1) Inhibitor compound 968 in ovarian cancer cells. The human ovarian cancer cell lines, HEY, SKOV3 and… Expand
Glutamine promotes ovarian cancer cell proliferation through the mTOR/S6 pathway
Glutamine is one of the main nutrients used by tumor cells for biosynthesis. Therefore, targeted inhibition of glutamine metabolism may have anti-tumorigenic implications. In the present study, we… Expand
Postoperative adjuvant chemotherapy combined with intracavitary brachytherapy achieved the equivalent survival compared with concurrent chemoradiotherapy in cervical cancer patients with…
- Hao Yu, Lin-lin Zhang, +6 authors X. Sheng
- Japanese journal of clinical oncology
- 1 August 2019
OBJECTIVES The current study was aimed to evaluate the efficacy and toxicity of postoperative adjuvant chemotherapy (CT) combined with intracavitary brachytherapy (ICRT) in cervical cancer patients… Expand