Lingliang Long

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In this work, we have successfully provided a novel strategy for the rational design and synthesis of a ratiometric fluorescent probe for hypochlorite. The strategy is based on the deoximation reaction, which has not yet been used in the fluorescent hypochlorite probe design. Interestingly, the probe showed a ratiometric fluorescent response to hypochlorite(More)
With the increasing concern of potential health and environmental risk, it is essential to develop reliable methods for transgenic soybean detection. Herein, a simple, sensitive and selective assay was constructed based on homogeneous fluorescence resonance energy transfer (FRET) between CdTe quantum dots (QDs) and multiwalled carbon nanotubes@graphene(More)
4-(1H-phenanthro[9,10-d]imidazol-2-yl)benzaldehyde 1 was rationally designed as a novel ratiometric fluorescent probe for cysteine and homocysteine. Upon addition of cysteine or homocysteine, notably, the probe displayed a very large (125 nm) hypsochromic shift in emission due to switching off intramolecular charge transfer. This large emission wavelength(More)
Phenanthroimidazole derivative 1 has been developed as a rare example of ratiometric fluorescent sensors for Fe(3+). Interestingly, upon treatment with Fe(3+), the sensor displayed a ratiometric fluorescent response with an enhancement of the ratios of emission intensities at 440 and 500 nm from 0.36 to 3.24. The detection range of the sensor for Fe(3+) is(More)
Compound 1 was designed and synthesized as a new fluorescent thiol probe. Probe 1 was constructed on the basis of the conjugate 1,4-addition of thiols to alpha,beta-unsaturated ketones. Notably, probe 1 has suitable water solubility, which allows the sensing assay to be performed in water. Probe 1 is highly sensitive for thiols with a 211-fold fluorescence(More)
Analyte-responsive fluorescent probes are valuable chemical tools for dissecting complex living systems. However, the major shortcoming of fluorescent probes is that once they enter the cells, control over them is basically lost. It is critical to regulate fluorescent probes in a spatial and temporal manner, as functions of biomolecules are spatiotemporal.(More)
Herein a ratiometric fluorescent Cu(2+) probe was rationally constructed in a straightforward manner with the concept of aldehyde group protection/deprotection. The probe showed a ratiometric fluorescent response to Cu(2+) with a large emission wavelength shift (>100 nm) and displayed high selectivity for Cu(2+) over other metal ions due to distinct(More)
In this work, compound 1 has been rationally designed and synthesized as a new fluorescent probe for biological thiols. Notably, probe 1 has almost no background fluorescence (Φf < 0.0001) in aqueous solutions; however, it exhibited fluorescence turn-on response to thiols with high sensitivity (a 246-fold fluorescence enhancement and a low detection limit(More)