Lingjie Zhou

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The intestinal absorptive characteristics and the efflux mechanisms of candesartan (CDS), a novel angiotensin II type 1 receptor blocker, were investigated. The Caco-2 cells were used as models of the intestinal mucosa to assess uptake and transport of CDS. The determination of CDS was performed by HPLC-Flu. In the Caco-2 cells, the uptake and absorptive(More)
Ulva linza is one of the causal species that result in the macroalgal blooms around Yellow Sea, China. The blooms have now become the world’s largest green tide, making great disaster for the ecosystem. We analyzed whole genome sequence of chloroplast for the first time (GenBank accession number KX058323). It was found that the annular-shape genome was made(More)
In this study, the influence of temperature and light intensity on the growth of seedlings and adults of four species of green tide algae (Ulvaprolifera, Ulvacompressa, Ulva flexuosa and Ulvalinza) from the Yellow Sea was evaluated. The results indicated that the specific growth rate (SGR) of seedlings was much higher than that of adults for the four(More)
Ulva flexuosa, one kind of green tide algae, has outbroken in the Yellow Sea of China during the past ten years. In the present study, we sequenced the chloroplast genome of U. flexuosa followed by annotation and comparative analysis. It indicated that the chloroplast genomes had high conservation among Ulva spp., and high rearrangement outside them. Though(More)
Ulva flexuosa, one kind of green tide algae, has outbroken in the Yellow Sea of China during the past 10 years. The blooms have now become the world’s largest green tide, making great disaster for the ecosystem. In the present study, we sequenced the mitochondrial genome of U. flexuosa for the first time (GenBank Accession Number KX455878). It was found(More)
Osteoporosis is a common problem in aged people and those with related diseases, such as inflammatory bowel diseases. Deregulation of vitamin D metabolism plays a role in the pathogenesis of osteoporosis. Micro RNA (miR) can regulate cytokine expression in cells. This study test a hypothesis that inflammatory cytokine interleukin (IL)-13 increases miR-19a(More)
A sensitive and specific method for the determination of bifendate in human plasma was developed, based on high-performance liquid chromatography (HPLC)-mass spectrometry (MS). The samples were extracted from plasma with diethyl ether, followed by separation and evaporation after addition of internal standard diazepam. The residue was reconstituted in(More)
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