Lingjiao Chen

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The mammalian target of rapamycin (mTOR) is a potentially important therapeutic target in a broad range of cancer types. mTOR inhibitors such as rapamycin and its analogs (rapalogs) have been proven effective as anticancer agents in non-small cell lung cancer (NSCLC), whereas they strongly enhance phosphorylation of eukaryotic translation initiation factor(More)
Providing machine learning (ML) over relational data is a mainstream requirement for data analytics systems. While almost all the ML tools require the input data to be presented as a single table, many datasets are multi-table, which forces data scientists to join those tables first, leading to data redundancy and runtime waste. Recent works on “factorized”(More)
We previously reported that expression of Flotillin 2 (Flot-2), a protein isolated from caveolae/lipid raft domains, increased significantly in nasopharyngeal carcinoma (NPC) compared with normal tissues. Signal transduction through epidermal growth factor receptors (EGFR) and Flot-2 play an important role in cancer development, but their precise role in(More)
In this paper we study the use of coding techniques to accelerate machine learning (ML). Coding techniques, such as prefix codes, have been extensively studied and used to accelerate low-level data processing primitives such as scans in a relational database system. However, there is little work on how to exploit them to accelerate ML algorithms. In fact,(More)
Nuclear localization of β-catenin is essential for the progression of various human cancers via transcriptional upregulation of downstream genes. The MAP kinase interacting serine/threonine kinase (MNK)-eukaryotic translation initiation factor 4E (eIF4E) axis has been reported to activate Wnt/β-catenin signaling, and CGP57380, an inhibitor of MNK kinases,(More)
Pleomorphic liposarcoma is an uncommon form of liposarcoma that rarely occurs in liver, especially the primary pleomorphic liposarcoma of liver. In the current work, we presented a case of primary pleomorphic liposarcoma of liver in a 43-year-old male with the history of abdominal tumor. Microscopically, the tumor consisted of pleomorphic spindle shaped(More)
Adrenal lipoadenoma is an extremely rare tumor. Only four cases have been reported so far. The authors reported a case of adrenal lipoadenoma in a 46-year-old man with the history of abdominal pain. The present case, manifesting as a nonfunctional adrenal tumor, is characteristically comprised of a mixture of mature adipocytes and adrenocortical cells. We(More)
Providing efficient machine learning (ML) analytics over relational data is a mainstream requirement for data management systems [2,5]. Several projects are building tools to closely integrate ML and data processing [3, 4, 9, 10]. Thus, there is a lot of interest in accelerating ML workloads using data management ideas. Recently, there are quite a few(More)
In this paper, a novel public key encryption scheme for large image is presented based on elliptic curve. As a public key encryption scheme, it does not need to exchange and distribute secret keys. Based on elliptic curve discrete logarithm problem (ECDLP), the scheme has high security. The simulation results show that the presented scheme is(More)
Lung cancer, with 80-85% being non-small cell lung cancer (NSCLC), is the leading cause of cancer-related death in both men and women. Long non-coding RNAs (lncRNAs), always defined as non-protein-coding RNA molecules longer than 200 nucleotides, are now thought as a new frontier in the study of human malignant diseases including NSCLC. As researches(More)