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Preparation of folate-modified pullulan acetate nanoparticles for tumor-targeted drug delivery
The purpose of this work was to develop a novel nano-carrier with targeting property to tumor. In this study, pullulan acetate (PA) was synthesized by the acetylation of pullulan to simplify theExpand
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Self-assembled nanoparticles of cholesterol-conjugated carboxymethyl curdlan as a novel carrier of epirubicin.
The purpose of this study was to develop nanoparticles made of cholesterol-conjugated carboxymethyl curdlan (CCMC) entrapping epirubicin (EPB) and establish their in vitro and in vivo potential. CCMCExpand
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Enhanced uptake and cytotoxity of folate-conjugated mitoxantrone-loaded micelles via receptor up-regulation by dexamethasone.
Folate conjugated amphiphilic polymeric micelles have attracted much attention for active targeted delivery of drugs in folate receptor α (FR-α) positive tumors. However, the efficacy improvement ofExpand
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Stability and in vivo evaluation of pullulan acetate as a drug nanocarrier
To develop pullulan acetate nanoparticles (PANs) as a drug nanocarrier, pullulan acetate (PA) was synthesized and characterized. Its acetylation degree determined by the proton nuclear magneticExpand
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A collagen mimetic peptide-modified hyaluronic acid hydrogel system with enzymatically mediated degradation for mesenchymal stem cell differentiation.
We have successfully designed and synthesized a biomimetic hydrogel system with maleimide-modified hyaluronic acid (HA) as the backbone and conjugated it to the collagen mimetic peptideExpand
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[Construction of a collagen gel dermis with improved biological property].
OBJECTIVE To improve the biological property of artificial skin. METHODS We have ameliorated Hansburgh and Middelkoop's method of manufacturing artificial dermis. The type I collagenase and DispaseExpand
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[The construction of two kinds of artificial bone and the comparison of their osteogenesis capability in vivo].
OBJECTIVE To construct artificial bone with collagen-hydroxyapatite (HA) or collagen-HA-chondroitin sulfate (CS) as the scaffolds, and observe their biological properties. METHODS The artificialExpand
In the article by Sandeep K. Sharma, Ashok Kumar, Reeti Chaudhary, Suman, C.S. Pundir, and Neeta Sehgal, which appeared in the previous issue of LABB 35(4) (entitled ‘‘Lactose Biosensor Based onExpand
[Study of collagen mimetic peptide's triple-helix structure and its thermostability by circular dichroism].
In the present study, the authors explore the triple-helix conformation and thermal stability of collagen mimetic peptides (CMPs) as a function of peptide sequence and/or chain length by circularExpand
[Structure and degradation property of the PVA-collagen complex drug membrane].
OBJECTIVE To investigate the structure and degradation property of the polyvinyl alcohol (PVA)-collagen complex drug membrane. METHODS Drug collagen membrane was complexed with PVA. The physicalExpand