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The remarkable diversity, glycosylation and conformational flexibility of the human immunodeficiency virus type 1 (HIV-1) envelope (Env), including substantial rearrangement of the gp120 glycoprotein upon binding the CD4 receptor, allow it to evade antibody-mediated neutralization. Despite this complexity, the HIV-1 Env must retain conserved determinants(More)
— Humans are adept at grasping different objects robustly for different tasks. Robotic grasping has made significant progress, but still has not reached the level of robustness or versatility shown by human grasping. It would be useful to understand what parameters (called grasp measures) humans optimize as they grasp objects, how these grasp measures are(More)
Arabidopsis thaliana seedlings undergo photomorphogenesis in the light and etiolation in the dark. Long Hypocotyl in Far-Red 1 (HFR1), a basic helix-loop-helix transcription factor, is required for both phytochrome A-mediated far-red and cryptochrome 1-mediated blue light signaling. Here, we report that HFR1 is a short-lived protein in darkness and is(More)
BACKGROUND Recent reports have indicated that microRNAs (miRNAs) play a critical role in malignancies, and regulations in the progress of adult leukemia. The role of miRNAs in pediatric leukemia still needs to be established. The purpose of this study was to investigate the aberrantly expressed miRNAs in pediatric acute leukemia and demonstrate miRNA(More)
—We present a novel and simple experimental method called physical human interactive guidance to study human-planned grasping. Instead of studying how the human uses his/her own biological hand or how a human teleoperates a robot hand in a grasping task, the method involves a human interacting physically with a robot arm and hand, carefully moving and(More)
BACKGROUND Hepatic ischemia-reperfusion (I/R) injury is a pivotal clinical problem occurring in many clinical conditions such as transplantation, trauma, and hepatic failure after hemorrhagic shock. Apoptosis and autophagy have been shown to contribute to cell death in hepatic I/R injury. Ethyl pyruvate, a stable and simple lipophilic ester, has been shown(More)
In this paper, a new corner detector is proposed based on evolution difference of scale pace, which can well reflect the change of the domination feature between the evolved curves. In Gaussian scale space we use Difference of Gaussian (DoG) to represent these scale evolution differences of planar curves and the response function of the corners is defined(More)
An efficient and novel technique is developed for detecting and localizing corners of planar curves. This paper discusses the gradient feature distribution of planar curves and constructs gradient correlation matrices (GCMs) over the region of support (ROS) of these planar curves. It is shown that the eigen-structure and determinant of the GCMs encode the(More)