Ling-Mei Yu

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OBJECTIVES Conduct, oppositional defiant, and attention deficit hyperactivity disorders, reflecting early antisociality and behavior dysregulation, are predictive of substance use disorders. Liabilities to these disorders share genetic and environmental variance. Parenting characteristics have been shown to influence development of antisociality, moderated(More)
Monoamine oxidase A (MAOA) locus is an attractive candidate for exploring genetic contribution to the variation in the risk for substance use disorders (SUD) because of its important role in the metabolism of neurotransmitters, including dopamine and serotonin. Prior findings have suggested an association of the MAOA gene with the risk for early onset SUD.(More)
In the search for genetic variants affecting liability to complex diseases, haplotype data have received increasing recognition. When there are more than a few haplotypes, one way to assess the association between disease status and haplotypes is to reconstruct their evolutionary history. To achieve that goal, we combine information from two sources: (1)(More)
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