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Lower ADD1 Gene Promoter DNA Methylation Increases the Risk of Essential Hypertension
The goal of our study is to investigate the contribution of promoter DNA methylation of α-adducin (ADD1) gene to the risk of essential hypertension (EH). Using the bisulphite pyrosequencing… Expand
Preliminary analysis of the association between methylation of the ACE2 promoter and essential hypertension.
The aim of the present study was to investigate whether methylation of the angiotensin I converting enzyme 2 (ACE2) promoter increases the risk of essential hypertension (EH). A total of 96 patients… Expand
Aberrant methylation of the GCK gene body is associated with the risk of essential hypertension.
Essential hypertension (EH) is commonly accompanied by a dysfunction of glucose metabolism. Glucokinase (GCK) is a key enzyme involved in glucose metabolism. The aim of the present study was to… Expand
Positive correlation between variants of lipid metabolism-related genes and coronary heart disease
Four gene variants related to lipid metabolism (including the rs562338 and rs503662 variants of the APOB gene, the rs7767084 variant of the LPA gene and the rs2246942 variant of the LIPA gene) have… Expand