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Given an integer $k$, a {\em representative skyline} contains the $k$ skyline points that best describe the tradeoffs among different dimensions offered by the full skyline. Although this topic has been previously studied, the existing solution may sometimes produce $k$ points that appear in an arbitrarily tiny cluster, and therefore, fail to be(More)
It is prevailingly thought that estrogen signaling is not involved in development of estrogen receptor (ER)-negative breast cancer. However, there is evidence indicating that ovariectomy prevents the development of both ER-positive and -negative breast cancer, suggesting that estrogen signaling is involved in the development of ER-negative breast cancer.(More)
Emerging evidence has shown the association of aberrantly expressed microRNAs (miRNAs) with tumor development and progression. However, little is known about the potential role of miRNAs in gastric carcinogenesis. Here, we performed miRNA microarray to screen miRNAs differentially expressed in the paired gastric cancer and their adjacent nontumor tissues(More)
In this paper, we will study a special Connected Dominating Set (CDS) problem — between any two nodes in a network, there exists at least one shortest path, all of whose intermediate nodes should be included in a special CDS, named Minimum rOuting Cost CDS (MOC-CDS). Therefore, routing by MOC-CDS can guarantee that each routing path between any pair(More)
Given a set <i>P</i> of <i>products</i>, a set <i>O</i> of <i>customers</i>, and a product <i>p</i> &#949; <i>P</i>, a <i>bichromatic reverse skyline</i> query retrieves all the customers in <i>O</i> that do not find any other product in <i>P</i> to be absolutely better than <i>p</i>. More specifically, a customer <i>o</i> &#949; <i>O</i> is in the(More)
Recently, we identified and cloned a membrane-based estrogen receptor (ER), ER-alpha 36, which is transcribed from a previously unidentified promoter in the first intron of the original ER-alpha gene. We cloned the 5' flanking region of ER-alpha 36 and found the cloned DNA sequence possessed strong promoter activity. A single transcription initiation site(More)
Some of the most serious diseases involve altered size and structure of the arterial wall. Elucidating how arterial walls are built could aid understanding of these diseases, but little is known about how concentric layers of muscle cells and the outer adventitial layer are assembled and patterned around endothelial tubes. Using histochemical, clonal, and(More)
It is prevailingly thought that the antiestrogens tamoxifen and ICI 182, 780 are competitive antagonists of the estrogen-binding site of the estrogen receptor-alpha (ER-α). However, a plethora of evidence demonstrated both antiestrogens exhibit agonist activities in different systems such as activation of the membrane-initiated signaling pathways. The(More)
In the present study, we determined the complete nucleotide sequence of the mitochondrial (mt) genome of tolai hare, Lepus tolai (Leporidae: Lepus) by using polymerase chain reaction (PCR) technique. The entire mtDNA sequence is 17,472 bp long and contains 13 protein-coding genes, two ribosomal RNA, 22 transfer RNA gens and one long non-coding region known(More)
The neurotoxin β-N-methylamino-l-alanine (BMAA) has been identified as an environmental factor triggering neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS) and Alzheimer's disease (AD). We investigated the possible vectors of BMAA and its isomers 2,4-diaminobutyric acid (DAB) and N-2(aminoethyl)glycine (AEG) in marine mollusks collected(More)