Lindsay W. Ludlow

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We formulated a "one-size-fits-all" model that predicts the energy requirements of level human walking from height, weight, and walking speed. Our three-component model theorizes that the energy expended per kilogram per stride is independent of stature at mechanically equivalent walking speeds. We measured steady-state rates of oxygen uptake of 78 subjects(More)
Aging is associated with a tissue degeneration phenotype marked by a loss of tissue regenerative capacity. Regenerative capacity is dictated by environmental and genetic factors that govern the balance between damage and repair. The age-associated changes in the ability of tissues to replace lost or damaged cells is partly the cause of many age-related(More)
NEW FINDINGS What is the central question of this study? A positive association between telomere length and exercise training has been shown in cardiac tissue of mice. It is currently unknown how each bout of exercise influences telomere-length-regulating proteins. We sought to determine how a bout of exercise altered the expression of(More)
We used external loading and surface inclination as experimental tools to: 1) test whether the metabolic cost of transporting body mass and torso mass are equal during walking, and 2) to develop an algorithm for estimating walking metabolism in the field. Rates of oxygen uptake were measured in ten physically active volunteers during constant-velocity(More)
Sensor-based predictions for walking energy expenditure require sufficiently versatile algorithms to generalize to a variety of conditions. Here we test whether our height-weight-speed (HWS) model validated across speed under level conditions is similarly accurate for loaded walking. We hypothesized that increases in walking energy expenditure would be(More)
Accurate prediction of the metabolic energy that walking requires can inform numerous health, bodily status, and fitness outcomes. We adopted a two-step approach to identifying a concise, generalized equation for predicting level human walking metabolism. Using literature-aggregated values we compared 1) the predictive accuracy of three literature(More)
The metabolic energy that human walking requires can vary by more than 10-fold, depending on the speed, surface gradient, and load carried. Although the mechanical factors determining economy are generally considered to be numerous and complex, we tested a minimum mechanics hypothesis that only three variables are needed for broad, accurate prediction:(More)
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