Linda Rafter

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The treatment of Epstein-Barr virus (EBV)-associated lymphoproliferative disease (PTLD) in EBV seronegative solid organ transplant recipients who acquire their EBV infection after engraftment poses a considerable challenge because of underlying immunosuppression that inhibits the virus-specific cytotoxic T cell (CTL) response in vivo. We have developed a(More)
1. Monarch caterpillars, Danaus plexippus (Linnaeus), feed on milkweed plants in the genus Asclepias and sequester cardenolides as an anti-predator defence. However, some predators are able to consume this otherwise unpalatable prey. 2. Chinese mantids, Tenodera sinensis (Saussure), were observed consuming monarch caterpillars by ‘gutting’ them (i.e.(More)
This article is a review of larval therapy and includes a case study that uses larval therapy in the treatment of complex leg ulcer wounds. Complex wounds require careful management from the multidisciplinary team and present clinicians with intricate challenges to save the limb. Wound-bed preparation and debridement needs to be as effective and(More)
BACKGROUND From previous work serum albumin is predictive of pressure ulcers over and above the Waterlow score. However the sub-scores of the Waterlow score were not available, and the accuracy of calculation of the total score was poor. This study has used sub-scores and is an order of magnitude larger. OBJECTIVES To compare serum albumin with Waterlow(More)
We have examined serum albumin as a risk factor for Clostridium difficile-associated diarrhoea (CDAD). CDAD and serum albumin are related. In a series of studies of patients with C. difficile, it has been found that serum albumin is lower in patients with CDAD and that it is associated with refractoriness. A fall in serum albumin is associated with the(More)
This article reports the findings of a small evaluation audit which compares the Dyna-Form Mercury Advance Mattress to that of the Softform Premier Active Mattress (a foam mattress with dynamic underlay). A small group of patients with similar co-morbidities who were an emergency admission were recruited to an evaluation audit. Their median age and Waterlow(More)
The NHS is driven by quality targets that permeate all specialties and care settings, and by the need for safety, efficiency and patient-centred care. Efficient care pathways need to be safe and indicated, and should offer measurable advantages and patient benefits as well as giving a treatment end point. Complex wounds require very careful management from(More)
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