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PURPOSE To determine whether retardation (change in polarization) measurements of healthy subjects and glaucoma patients obtained by using a confocal scanning laser polarimeter correspond to known properties of the nerve fiber layer. METHODS A polarimeter, an optical device used to measure the change in linear polarization of light (retardation), was(More)
PURPOSE To compare the ability of optical coherence tomography retinal nerve fiber layer (RNFL), optic nerve head, and macular thickness parameters to differentiate between healthy eyes and eyes with glaucomatous visual field loss. DESIGN Observational case-control study. METHODS Eighty-eight patients with glaucoma and 78 healthy subjects were included.(More)
PURPOSE To evaluate RTVue spectral-domain optical coherence tomography (OCT) (Optovue Inc, Fremont, California, USA) reproducibility and to assess agreement with Stratus time-domain OCT (Carl Zeiss Meditec, Dublin, California, USA) measurements. DESIGN Observational clinical study. METHODS Scans were obtained from both eyes of all participants 3 times(More)
OBJECTIVE To compare the abilities of current commercially available versions of 3 optical imaging techniques: scanning laser polarimetry with variable corneal compensation (GDx VCC), confocal scanning laser ophthalmoscopy (HRT II [Heidelberg Retina Tomograph]), and optical coherence tomography (Stratus OCT) to discriminate between healthy eyes and eyes(More)
OBJECTIVE To quantitatively assess and compare the thickness of the retinal nerve fiber layer (RNFL) in ocular hypertensive eyes with normal and glaucomatous eyes using the Optical Coherence Tomograph (OCT 2000, software version A4X1; Humphrey Instruments, San Leandro, Calif). METHODS The mean RNFL thickness of ocular hypertensive (n = 28) eyes was(More)
BACKGROUND/AIMS To evaluate spectral-domain (SD) optical coherence tomography (OCT) reproducibility and assess the agreement between SD-OCT and Time-Domain (TD) OCT retinal nerve fibre layer (RNFL) measurements. METHODS Three Cirrus-SD-OCT scans and one Stratus-TD-OCT scan were obtained from Diagnostic Innovations in Glaucoma Study (DIGS) healthy(More)
PURPOSE To determine whether central corneal thickness (CCT) is a risk factor for visual field loss development among patients diagnosed with preperimetric glaucomatous optic neuropathy (GON). DESIGN Observational cohort study. METHODS The study included 98 eyes of 98 patients with GON, with a mean follow-up time of 4.3 +/- 2.7 years. Diagnosis of GON(More)
A population-based study found an overall incidence rate of symptomatic retinal vein occlusion (RVO) in a 4-year period to be 2.14 per 1,000 in the 40 years and over age group. When cases found among glaucoma clinic patients were separated from the remainder of the population there was marked difference in the incidence rate of RVO in the same time period(More)
OBJECTIVE To determine which retinal nerve fiber layer (RNFL) measures obtained with scanning laser polarimetry are most useful in detecting early to moderate glaucomatous visual field loss. SUBJECTS AND METHODS One eye from 84 healthy individuals and 83 patients with early to moderate glaucomatous visual field loss (167 eyes) was assessed with a scanning(More)
OBJECTIVE To compare the ability of scanning laser polarimetry (SLP) to discriminate between healthy and glaucomatous eyes with manufacturer-assumed fixed and subject-specific variable corneal polarization magnitude (CPM) and corneal polarization axis (CPA) values. METHODS An SLP was modified to enable the measurement of CPM and CPA values so that(More)