Linda M. Wilson

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The use of trade, firm, or corporation names in this publication is for information only and does not constitute an endorsement by the U.S. Department of Agriculture. The U.S. Department of Agriculture (USDA) prohibits discrimination in all its programs and activities on the basis of race, color, national origin, sex, religion, age, disability, political(More)
Male Sprague-Dawley rats (180 g) and 28-day-old Single Comb White Leghorn Cockerels (300 g) were orally dosed with deoxynivalenol (DON) at 2.5 mg kg-1 body weight. In the first experiment, whole brains were collected at 2, 6, 12, 24 and 48 hours after the toxin treatment and analyzed for brain biogenic monoamines by high-performance liquid chromatography(More)
the effects of unsignalled, inescapable prior shock exposure (PSE) on shock-motivated Pavlovian conditioned heart rate (HR) decelerations in rats. Both studies involved 2 CS-US contingencies (paired and unpaired) and 2 preshock treatments (preshock and no preshock). The 2 designs differed in the type of immobilization procedures to which the rats were(More)
Biochemical abnormalities in the hypothalamus of the genetically obese (C57B1/6J, ob/ob) mouse, including increased levels of endogenous norepinephrine (NE) in the paraventricular nucleus (PVN) and reduced medial hypothalamic NE metabolism, have been cited as evidence of a CNS defect contributing to altered caloric intake in this genetic strain. In the(More)
The use of trade, firm, or corporation names in this publication is for information only and does not constitute an endorsement by the U.S. Department of Agriculture. The U.S. Department of Agriculture (USDA) prohibits discrimination in all its programs and activities on the basis of race, color, national origin, sex, religion, age, disability, political(More)
The use of trade, firm, or corporation names in this publication is for information only and does not constitute an endorsement by the U.S. Department of Agriculture. The U.S. Department of Agriculture (USDA) prohibits discrimination in all its programs and activities on the basis of race, color, national origin, sex, religion, age, disability, political(More)
Chronically lower colonic temperatures (TcS) of genetically-obese (ob/ob) mice at ambient temperatures below thermoneutrality have led to speculation that these mutants regulate a lowered thermal setpoint relative to lean mice. Previous experiments, however, have not provided an opportunity for obese mice to exhibit compensatory thermoregulatory behaviors(More)
The effects of intracerebroventricular (ICV) administration of 5-hydroxytryptamine creatinine sulphate complex (5-HT), 35-140 nmol, on food intake in genetically obese (ob/ob) and lean mice were investigated. 5-HT (70-140 nmol) decreased feeding in a dose-related manner on 1 h and 2 h postinjection measures. Intake in lean mice was reduced by over 70% of(More)
Genetically obese mice (B6.Cg-lep(ob)) manifest decreased responses to noxious thermal stimuli (hotplate test) suggesting endogenous analgesia (Roy et al., 1981). To examine further the analgesic response of these mice, we conducted 4 experiments. Experiment 1 assessed the response of ob/ob mice to tail flick, another noxious thermal test. Tail-flick(More)