Linda J Eaton

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Francisella tularensis (Ft), a Gram-negative intracellular bacterium, is the etiologic agent of tularemia. Although attenuated for humans, i.p. infection of mice with <10 Ft live vaccine strain (LVS) organisms causes lethal infection that resembles human tularemia, whereas the LD50 for an intradermal infection is >10(6) organisms. To examine the(More)
We previously showed in vitro hydrolysis of outer membrane proteins by lysosomal proteases and purified elastase. In this study we examined the in vivo relevance of the previous studies. Outer membranes were obtained from Neisseria gonorrhoeae type 3 (strain GC7) by LiCl2 extraction. Some preparations were labeled with 125I. Phagocytizable particles were(More)
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