Linda H. Harpole

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CONTEXT Few depressed older adults receive effective treatment in primary care settings. OBJECTIVE To determine the effectiveness of the Improving Mood-Promoting Access to Collaborative Treatment (IMPACT) collaborative care management program for late-life depression. DESIGN Randomized controlled trial with recruitment from July 1999 to August 2001. (More)
CONTEXT Depression and arthritis are disabling and common health problems in late life. Depression is also a risk factor for poor health outcomes among arthritis patients. OBJECTIVE To determine whether enhancing care for depression improves pain and functional outcomes in older adults with depression and arthritis. DESIGN, SETTING, AND PARTICIPANTS(More)
BACKGROUND Late life depression can be successfully treated with antidepressant medications or psychotherapy, but few depressed older adults receive effective treatment. RESEARCH DESIGN A randomized controlled trial of a disease management program for late life depression. SUBJECTS Approximately 1,750 older adults with major depression or dysthymia are(More)
STUDY OBJECTIVES To determine the test performance characteristics of transbronchial needle aspiration (TBNA), transthoracic needle aspiration (TTNA), endoscopic ultrasound-guided needle aspiration (EUS-NA), and mediastinoscopy in staging non-small cell lung cancer (NSCLC). DESIGN, SETTING, AND PARTICIPANTS Systematic search of MEDLINE, HealthStar, and(More)
STUDY OBJECTIVES To provide an evidence-based background for developing the American College of Chest Physicians (ACCP) lung cancer guidelines, a systematic review of the literature was performed to identify published lung cancer guidelines and evaluate their quality. DESIGN, SETTING, AND PARTICIPANTS A systematic search was performed for relevant(More)
OBJECTIVE To determine the long term effectiveness of collaborative care management for depression in late life. DESIGN Two arm, randomised, clinical trial; intervention one year and follow-up two years. SETTING 18 primary care clinics in eight US healthcare organisations. Patients 1801 primary care patients aged 60 and older with major depression,(More)
CONTEXT Depression is a leading cause of functional impairment in elderly individuals and is associated with high medical costs, but there are large gaps in quality of treatment in primary care. OBJECTIVE To determine the incremental cost-effectiveness of the Improving Mood Promoting Access to Collaborative Treatment (IMPACT) collaborative care management(More)
PURPOSE Our objective was to examine the relative association of depression severity and chronicity, other comorbid psychiatric conditions, and coexisting medical illnesses with multiple domains of health status among primary care patients with clinical depression. METHODS We collected cross-sectional data as part of a treatment effectiveness trial that(More)
OBJECTIVES To determine the effect of collaborative care management for depression on physical functioning in older adults. DESIGN Multisite randomized clinical trial. SETTING Eighteen primary care clinics from eight healthcare organizations. PARTICIPANTS One thousand eight hundred one patients aged 60 and older with major depressive disorder. (More)
OBJECTIVE Inappropriate utilization of diagnostic testing has been well documented. The purpose of this study was to measure the impact of presenting real time, evidence-based critiques about the appropriateness of abdominal radiograph (KUB) orders on physician decision making. DESIGN Prospective trial where evidence-based critiques were presented to(More)