• Publications
  • Influence
Family Income, Parental Education and Brain Structure in Children and Adolescents
TLDR
Investigation of relationships between socioeconomic factors and brain morphometry among a cohort of typically developing individuals suggests that income relates most strongly to brain structure among the most disadvantaged children.
Loss of Dopamine Transporters in Methamphetamine Abusers Recovers with Protracted Abstinence
TLDR
It is suggested that protracted abstinence may reverse some of methamphetamine-induced alterations in brain DA terminals, and neuropsychological tests did not improve to the same extent as during short abstinence, which suggests that the increase of the DA transporters was not sufficient for complete function recovery.
Evidence for long-term neurotoxicity associated with methamphetamine abuse
TLDR
Evidence for long-term neuronal damage in abstinent methamphetamine users is provided by the reduced N-acetylaspartate on 1H MRS, which was reduced significantly in the basal ganglia and frontal white matter of methamphetamine users compared with control subjects.
Multi-contrast human neonatal brain atlas: Application to normal neonate development analysis
TLDR
The development of neonatal brain atlases with detailed anatomic information derived from DTI and co-registered anatomical MRI and a diffeomorphic transformation is reported, which was able to normalize Neonatal brain images to the atlas space and three-dimensionally parcellate images into 122 regions.
Neuroanatomical Assessment of Biological Maturity
TLDR
This work demonstrates that developmental brain phase can be assessed with much greater precision than has been possible using other biological measures, and reveals for the first time a latent phenotype in the human brain for which maturation timing is tightly controlled.
The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository
TLDR
The recruiting and screening of the children are described and a brief overview of the assessments performed, the imaging methods applied, the genetic data produced, and the numbers of cases for whom different data types are available are given.
Smaller subcortical volumes and cognitive deficits in children with prenatal methamphetamine exposure
TLDR
Compared with the control group, children exposed to Meth prenatally exhibit smaller subcortical volumes and associated neurocognitive deficits and preliminary findings suggest prenatal Meth exposure may be neurotoxic to the developing brain.
Unified structural equation modeling approach for the analysis of multisubject, multivariate functional MRI data
TLDR
This work proposes a two‐stage unified SEM plus GLM (General Linear Model) approach for the analysis of multisubject, multivariate functional magnetic resonance imaging (fMRI) time series data with subject‐level covariates to examine the impact of these covariates on effective connectivity via a GLM.
Psychobiologic effects of 3,4-methylenedioxymethamphetamine in humans: methodological considerations and preliminary observations
TLDR
The background, methodology and preliminary findings of the first FDA approved Phase I study prospectively evaluating the effects of MDMA administration in humans, using a randomized, double-blind methodologic design are discussed.
Gender differences in the functional organization of the brain for working memory
TLDR
Gender differences in brain activation during working memory tasks were examined with fMRI and show a highly significant (p < 0.001) gender differences in the functional organization of the brain for working memory.
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