Linda C Harris

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BACKGROUND Deregulated expression of oncogenes such as MYC and PAX3-FKHR often occurs in rhabdomyosarcomas. MYC can enhance cell proliferation and apoptosis under specific conditions, whereas PAX3-FKHR has only been described as anti-apoptotic. RESULTS In order to evaluate how MYC and PAX3-FKHR oncogenes influenced p53-mediated apoptosis, rhabdomyosarcoma(More)
  • James L Coneyrs, Director, James L Conyers, Malachi D Crawford, Paul H L Easterling, Angela Williams-Phillips +10 others
  • 2008
Director's Message t he 2006-2007 academic year was filled with much activity, advancement, forward thinking and proactive growth for the African American Studies program at the University of Houston. With the continuation of our seminar lecture series and the impetus of the hip hop lecture series archive, AAS sustained its tradition of providing the campus(More)
A synthetic oligonucleotide containing ribozyme sequences targeted to the S' region of the human O6-methylguanine-DNA methyltransferase (MGMT) inKNA has been constructed. This ribozyme demonstrates cleav age activity I'Mvitro in the presence of Mg2+. To determine whether this ribozyme can function in vivo, HeLa CCL2 cells were transfected with a mammalian(More)
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