Linda Buckner

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Aberrant activation of Rho family GTPases has been implicated in the pathogenesis of leukemia. However, the RhoGEFs that regulate the enhanced activation of RhoGTPases during leukemia progression remain elusive. PLEKHG2 is a novel Dbl family RhoGEF that was originally identified as a gene upregulated in a leukemia mouse model, and later shown to be(More)
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