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OBJECTIVE We describe the clinical application and utility of high-resolution magnetic resonance neurography (MRN) techniques to image the normal fascicular structure of peripheral nerves and its distortion by mass lesions or trauma in the lower extremity. METHODS MRN images were obtained using a standard 1.5 Tesla magnet and custom built phased-array(More)
OBJECT The aim of this study was to determine the incidence and clinical significance of complications related to preoperative embolization of cerebral arteriovenous malformations (AVMs) with silk sutures as documented on postprocedure computerized tomography (CT) scans. METHODS The CT scans were obtained within 12 to 24 hours after 221 (96%) of 230(More)
PURPOSE To identify the optimal imaging planes for magnetic resonance (MR) evaluation of the sacral plexus (SP) and proximal sciatic nerve (SN). MATERIALS AND METHODS The SPs of 10 health adult volunteers were prospectively studied with T1-weighted MR imaging with custom-built pelvic phased-array coils. The conspicuity of 12 anatomic characteristics(More)
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), one of the most prevalent and procarcinogenic compounds in tobacco, is bioactivated by respiratory cytochrome P450 (CYP) 2A13, forming DNA adducts and initiating lung cancer. CYP2A13 inhibition offers a novel strategy for chemoprevention of tobacco-associated lung cancer. Twenty-four analogs of a(More)
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