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BACKGROUND diabetes and hypertension are two highly prevalent diseases in the old population. They are highly related such that comorbidity is common. OBJECTIVES to examine (i) the independent impact of the respective diseases on cognitive decline in very old age and (ii) the interactive impact of the two diseases on cognitive decline. SUBJECTS 258(More)
BACKGROUND The purpose of this study was to examine if Type 2 diabetes mellitus is a risk factor for dementia in very old age, specifically for Alzheimer's disease (AD) and vascular dementia (VaD). METHODS We evaluated the risk of dementia in relation to Type 2 diabetes using a population-based sample of 702 individuals aged 80 years and older (mean age(More)
We examined change in neuropsychological test performance related to type 2 diabetes mellitus across a 6-year interval. A population-based sample of 274 elderly participants (36 with diabetes and 238 without diabetes) was examined at four occasions at a 2-year interval. The participants were 80-93 years of age (M = 82.8 years) and without dementia at(More)
The purpose of this study was to assess the relative importance of age, gender, and education on episodic memory functioning in a population-based sample of healthy individuals, between 90 and 100 years of age. A total of 80 persons completed a face recognition task, immediate and delayed word recall, object recall, and the Mini-Mental State Examination.(More)
BACKGROUND The relationship between vitamin status and cognitive functioning has been addressed in several recent studies with inconclusive results. The purpose of this study was to examine separate and combined effects of serum vitamin B12 and folic acid on episodic memory functioning in very old age. METHODS Four study groups were selected from a(More)
PURPOSE This study describes the Swedish debate on the role of family and state in care of elderly persons. It provides empirical evidence on the shifting balance of family, state, and market in the total panorama of elderly care. DESIGN AND METHODS Secondary analysis of older (1954) and more recent data sources (1994 and 2000) is used to assess living(More)
The purpose of this study was to examine the cognition-survival relationship among nondemented individuals in late life. The longitudinal design included three examinations at 2-year intervals. At baseline, 466 individuals (age range = 80-98) were examined. During the 6 years of follow-up, 206 individuals died. Four survival groups were defined on the basis(More)
BACKGROUND High midlife body mass index (BMI) has been linked to a greater risk of dementia in late life, but few have studied the effect of BMI across midlife on cognitive abilities and cognitive change in a dementia-free sample. METHODS We investigated the association between BMI, measured twice across midlife (mean age 40 and 61 years, respectively),(More)
Obesity is a health problem that has reached epidemic proportions. Given the high prevalence of obesity, even a small adverse impact of obesity on cognitive aging might have a serious effect on public health. The purpose of this systematic review was to examine the relation between obesity and cognitive function in late life among persons not diagnosed with(More)
OBJECTIVE Type 2 diabetes confers a greater excess risk of cardiovascular disease in women than in men. Diabetes is also a risk factor for dementia, but whether the association is similar in women and men remains unknown. We performed a meta-analysis of unpublished data to estimate the sex-specific relationship between women and men with diabetes with(More)