Lina María García

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BACKGROUND Mounting evidence links systemic and local inflammatory cytokine production to myocardial dysfunction and injury occurring during ischemia-reperfusion, cardiopulmonary bypass, and heart failure. Phosphodiesterase inhibitors (PDEIs), used frequently in these states, can modulate inflammatory signaling. The mechanisms for these effects are unclear.(More)
OBJECTIVE We hypothesized that the alterations in vasomotor tone and adaptive remodeling responses that occur in the circulation because of hypoxia were dependent on changes in cell to cell communication through regulation of gap junction protein expression and function. Consequently, we studied the amount, distribution, and permeability of the principal(More)
Objectives To explore the relationships among social, economic, environmental, and health services determinants of tuberculosis (TB) morbidity and mortality, and to identify the mechanisms that mediate such associations in countries of Latin America and the Caribbean (LAC). Methods This was an ecological study of 26 LAC countries that had accurate data(More)
UNLABELLED Cerebral atrophy is a common finding in patients infected with the Human Immunodeficiency Virus (HIV), particularly in patients with dementia. This disease shows neocortical compromise in late stages as well as compromise in the basal ganglia in early or asyntomatic phases. OBJECTIVE Evaluate changes in total brain volume, caudate nucleus(More)
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