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With the extensive applications of the Architecture Analysis and Design Language (AADL), how to use AADL to create platform-independent models (PIMs) is becoming a research focus. Most applications use UML or SysML to create PIMs, and then use the conversion rules to convert to AADL models, but how to ensure the consistency of the models is a challenge.(More)
Cysteine-rich receptor kinases (CRKs) belong to the receptor-like kinase family. Little is known about CRK genes in wheat. We isolated a wheat CRK gene TaCRK1 from Rhizoctonia cerealis-resistant wheat CI12633 based on a differentially expressed sequence identified by RNA-Sequencing (RNA-Seq) analysis. TaCRK1 was more highly expressed in CI12633 than in(More)
Bread wheat (Triticum aestivum L.) is a major staple crop in the world. Grain weight is a major factor of grain yield in wheat, and the identification of candidate genes associated with grain weight is very important for high-yield breeding of wheat. TaGW2 is an orthologous gene of rice OsGW2 that negatively regulates the grain width and weight in rice.(More)
Synapses are essential components of neurons and allow information to travel coordinately throughout the nervous system to adjust behavior to environmental stimuli and to control body functions, memories, and emotions. Thus, optimal synaptic communication is required for proper brain physiology, and slight perturbations of synapse function can lead to brain(More)
A novel method of the computation of the discrete fractional cosine transform (DFRCT) based on adaptive Least Mean Square (LMS) algorithm is proposed. The weight vectors are adjusted or adapted in accord with the least mean square error between the ldquodesired responserdquo and the reconstructed signal. It can be proved that the weight vector is in(More)
This paper presents a novel 3D surface texture classification method based on self-similarity maps which are calculated directly from raw captured texture images. 3D surface textures have special properties for they are sensitive to illumination and view conditions. Some previous classification methods which are illumination invariant or rotation invariant(More)
Take-all (caused by the fungal pathogen Gaeumannomyces graminis var. tritici, Ggt) and common root rot (caused by Bipolaris sorokiniana) are devastating root diseases of wheat (Triticum aestivum L.). Development of resistant wheat cultivars has been a challenge since no resistant wheat accession is available. GmPGIP3, one member of(More)
Huntington Disease (HD) is caused by an abnormal expansion of polyQ tract in the protein named huntingtin (Htt). HD pathology is featured by accumulation and aggregation of mutant Htt in striatal and cortical neurons. Aberrant Htt degradation is implicated in HD pathogenesis. The aim of this study was to investigate the regulatory role of chaperone-mediated(More)
Diffuse intrinsic pontine glioma (DIPG) is a fatal childhood cancer. We performed a chemical screen in patient-derived DIPG cultures along with RNA-seq analyses and integrated computational modeling to identify potentially effective therapeutic strategies. The multi-histone deacetylase inhibitor panobinostat demonstrated therapeutic efficacy both in vitro(More)