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BACKGROUND Air pollution exposure increases cardiovascular morbidity and mortality and is a major global public health concern. OBJECTIVES We investigated the benefits of reducing personal exposure to urban air pollution in patients with coronary heart disease. METHODS In an open randomized crossover trial, 98 patients with coronary heart disease walked(More)
OBJECTIVES Lifestyle factors are well-known important modifiable risk factors for obesity; the association between tobacco smoking and central obesity, however, is largely unknown in the Chinese population. This study examined the relationship between smoking and central obesity in 0.5 million Chinese adults, a population with a low prevalence of general(More)
PURPOSE Chronic exposure to heroin induced cerebral structural abnormalities may underlie heroin-related behaviors. The aim of this study was to: (1) identify cerebral structural abnormalities in heroin-dependent individuals (HDIs) by an automated and unbiased morphometric technique. (2) Define the correlation between these cerebral structural abnormalities(More)
BACKGROUND Chinese men now smoke more than a third of the world's cigarettes, following a large increase in urban then rural usage. Conversely, Chinese women now smoke far less than in previous generations. We assess the oppositely changing effects of tobacco on male and female mortality. METHODS Two nationwide prospective studies 15 years apart recruited(More)
OBJECTIVE To examine the associations between the regular consumption of spicy foods and total and cause specific mortality. DESIGN Population based prospective cohort study. SETTING China Kadoorie Biobank in which participants from 10 geographically diverse areas across China were enrolled between 2004 and 2008. PARTICIPANTS 199,293 men and 288,082(More)
BACKGROUND In recent years, problems like insufficient coordination, low efficiency, and heavy working load in national communicable disease surveillance systems in China have been pointed out by many researchers. To strengthen the national communicable disease surveillance systems becomes an immediate concern. Since the World Health Organization has(More)
INTRODUCTION Blood pressure is a major cause of cardiovascular disease (CVD) and both may increase as outdoor temperatures fall. However, there are still limited data about seasonal variation in blood pressure and CVD mortality among patients with prior-CVD. METHODS We analysed data on 23 000 individuals with prior-CVD who were recruited from 10 diverse(More)