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BACKGROUND Myeloid-derived suppressor cells (MDSCs) are among the major obstacles that adjuvants for cancer vaccines have to overcome. These cells cross-present tumor-associated antigens (TAA) to(More)
Leukopenia is a severe condition resulting from both pathological processes and some treatments, like chemotherapy in cancer patients. However, the activation of the patient immune system is required(More)
A perturbation of normal myelopoiesis, as a consequence of tumor growth and development; leads to the proliferation and accumulation of myeloid derived suppressor cells (MDSC), which impair T-cell(More)