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This study developed a simple, efficient method for producing racemic β-phenylalanine acid (BPA) and its derivatives via the enantioselective acylation catalyzed by the penicillin G acylase from Alcaligenes faecalis (Af-PGA). When the reaction was run at 25°C and pH 10 in an aqueous medium containing phenylacetamide and BPA in a molar ratio of 2:1, 8 U/mL(More)
The antioxidant activities of water extract (WE), ethanol extract (EE), residue water extract (RWE) and petroleum ether (PF), ethyl acetate (EF), n-BuOH (BF) and water (WF) fractions of the ethanol extract from Eupatorium Lindley DC were investigated for the first time. Total phenolics content, DPPH radical scavenging activities, superoxide radical(More)
ETHNOPHARMACOLOGICAL RELEVANCE Mahonia bealei has a long history of medical use in traditional Chinese medicine for the treatment of inflammatory-associated diseases. Despite numerous phytochemical and pharmacological studies, there is a lack of systematic studies to understand the cellular and molecular mechanisms of the anti-inflammatory activity of this(More)
Apigenin-7-O-β-D-glucuronide (AG), an active flavonoid derivative isolated from the agricultural residue of Juglans sigillata fruit husks, possesses multiple pharmacological activities, including anti-oxidant, anti-complement, and aldose reductase inhibitory activities. To date, no report has identified the anti-inflammatory mechanisms of AG. This study was(More)
Snakes are an effective approach to image segmentation. However, self-looping is a very common problem that makes snakes fail to work well in certain circumstances. In order to achieve robust segmentation, this paper introduces the loop-free snakes based on an attractable active contour model that overcomes several problems of conventional snake model whale(More)
A new method for extracting the boundary of the region of interest (ROI) from motion affected magnetic resonance images (MRI) is presented. An image pre-processing stage is included to suppress prominent ghost artifacts and excessive blurring in the background, in order to facilitate the contour extraction algorithm. The pre-processing stage consists of a(More)