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Methylmercury (MeHg), as a well-known neurotoxicant, has been implicated to induce massive neurodegeneration. Pyrroloquinoline quinone (PQQ) is a novel redox cofactor and also exists in various plants and animal tissues. In vivo as well as in vitro experimental studies have shown that PQQ functions as an essential nutrient or antioxidant. In this study, we(More)
Obesity is a complex metabolic disease, which causes serious impairment to the health of people. This study aimed to determine the influence of different-doses of soy isoflavones (SIF) on testicular morphology, testosterone levels and the expression of genes and proteins related to testosterone synthesis in diet-induced obesity (DIO) male rats. We used(More)
Oxidative stress has been implicated in a range of neurodegenerative diseases, in particular, Parkinson's disease (PD). However, the pathogenic mechanism of its influence on PD progression remains unclear. In order to clarify this, PD models are generated by 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intramuscular injection in eight rhesus monkeys.(More)
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