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Three terpyridine derivatives L1-L3 and their Pt(II) complexes 1-3 have been prepared, the binding interactions with human telomeric (h-telo) and the promoter c-kit2 and c-myc G-quadruplex DNAs were investigated. All the ligands and the complexes are potent stabilisers of the G-quadruplex structures and exhibit the G-quadruplex selectivity over duplex. The(More)
The multi-subunit complex Elongator interacts with elongating RNA polymerase II (RNAPII) and is thought to facilitate transcription through histone acetylation. Elongator is highly conserved in eukaryotes, yet has multiple kingdom-specific functions in diverse organisms. Recent genetic studies performed in Arabidopsis have demonstrated that Elongator(More)
Anthocyanins are ubiquitous plant secondary products that possess nutritive values and serve essential functions in plant defense. The purple kale (Brassica oleracea var. acephala f. tricolor) BoPAP1 gene, which encodes a MYB transcription factor associated with anthocyanin biosynthesis, was introduced into tomato (Solanum lycopersicum) under the control of(More)
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