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Diurnal alterations in circadian genes and peptides in major depressive disorder before and after escitalopram treatment
BACKGROUND Strong links exist between circadian disturbances and some of the most characteristic symptoms of clinical major depressive disorder (MDD). However, changes in the expression of clockExpand
  • 35
  • 1
[Emodin alleviates pulmonary fibrosis through inactivation of TGF-β1/ADAMTS-1 signaling pathway in rats].
Objective To explore the role of transforming growth factor-β1 (TGF-β1)/a disintegrin-like and metalloproteinase with thrombospondin type 1 motif (ADAMTS-1) signaling pathway in emodin'sExpand
  • 3
[Unsaturated fatty acid of Actinidia chinesis Planch seed oil enhances the antioxidative stress ability of rats with pulmonary fibrosis through activating Keap 1/Nrf 2 signaling pathway].
OBJECTIVE To observe the effects of unsaturated fatty acid of Actinidia chinesis Planch(USFA-ACP) seed oil on bleomycin-induced pulmonary fibrosis in rats, and to explore whether the effect isExpand
  • 1
[miR-21 promotes pulmonary fibrosis in rats via down-regulating the expression of ADAMTS-1].
Objective To observe the effect of miR-21 on bleomycin-induced pulmonary fibrosis in rats, and explore the related mechanism. Methods Peripheral blood was collected from idiopathic pulmonary fibrosisExpand
  • 5
[Protective effect of hydrogen sulfide on mice with experimental viral myocarditis and its mechanism].
  • H. Qian, Lijing Liu
  • Medicine
  • Xi bao yu fen zi mian yi xue za zhi = Chinese…
  • 1 July 2014
OBJECTIVE To explore the protective effect of hydrogen sulfide (H2S) on viral myocarditis (VMC) mice and its mechanism. METHODS Seventy BALB/c mice were randomly divided into 4 groups: normalExpand
  • 2
[The poor chemotherapeutic efficacy in lung adenocarcinoma overexpressing c-Src and nucleophosmin/B23(NPM1)].
Objective To observe the expressions of c-Src protein and nucleophosmin/B23 (NPM1) protein in lung adenocarcinoma tissues and explore their relationships with chemotherapeutic efficacy. Methods TheExpand
  • 3
[miR-27a-3p inhibits pulmonary fibrosis by blocking Wnt3a/β-catenin pathway in rats].
Objective To observe the effect of miR-27a-3p on bleomycin A5-induced pulmonary fibrosis (PF) in rats and explore the underlying mechanism. Methods Forty-five male SD rats were randomly divided intoExpand
  • 1
[Up-regulation of miR-21 promotes cell proliferation and collagen synthesis in pulmonary fibroblasts].
  • Lijing Liu, H. Qian
  • Biology, Medicine
  • Xi bao yu fen zi mian yi xue za zhi = Chinese…
  • 1 July 2015
OBJECTIVE To explore the expression of miR-21 in lung tissues of mice with pulmonary fibrosis, and its role in proliferation, trans-differentiation and collagen synthesis of pulmonary fibroblasts. Expand
  • 2
[Alpinetin promotes the binding of PPAR and methyltransferase].
Objective To screen the nucleus located-methyltransferase in murine macrophages (RAW246.7 cells) after peroxisome proliferator-activated receptors (PPAR) is activated by alpinetin so as to prove theExpand
  • 1
[Unsaturated fatty acid of Actinidia chinesis planch seed oil (kiwi fruit essence) inhibits growth and metastasis of transplanted tumor in lung adenocarcinoma mice by up-regulating EHD2 expression].
Objective To observe the role of Eps15 homology domain containing protein 2 (EHD2) in the inhibitive effects of unsaturated fatty acid of Actinidia chinesis planch seed oil (kiwi fruit essence) onExpand