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Negative allosteric regulation of Enterococcus faecalis small alarmone synthetase RelQ by single-stranded RNA
- Jelena Beljantseva, P. Kudrin, +4 authors V. Hauryliuk
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 20 March 2017
Significance Bacteria regulate their intracellular environment through two ubiquitous posttranscriptional regulatory mechanisms: enzymatic synthesis of small signaling molecules that allosterically… Expand
Lack of RsmA-Mediated Control Results in Constant Hypervirulence, Cell Elongation, and Hyperflagellation in Pectobacterium wasabiae
The posttranscriptional regulator RsmA controls the production of plant cell wall degrading enzymes (PCWDE) and cell motility in the Pectobacterium genus of plant pathogens. In this study the… Expand
Cationic bactericidal peptide 1018 does not specifically target the stringent response alarmone (p)ppGpp
The bacterial stringent response is a key regulator of bacterial virulence, biofilm formation and antibiotic tolerance, and is a promising target for the development of new antibacterial compounds.… Expand
Type II quorum sensing regulates virulence in Erwinia carotovora ssp. carotovora.
Quorum sensing is a process by which bacteria communicate using secreted chemical signaling molecules called autoinducers. In this study, the opportunistic plant pathogen Erwinia carotovora ssp.… Expand
The Rcs phosphorelay modulates the expression of plant cell wall degrading enzymes and virulence in Pectobacterium carotovorum ssp. carotovorum.
Production of plant cell wall degrading enzymes, the major virulence factors of soft-rot Pectobacterium species, is controlled by many regulatory factors. Pectobacterium carotovorum ssp. carotovorum… Expand
A role for the Rcs phosphorelay in regulating expression of plant cell wall degrading enzymes in Pectobacterium carotovorum subsp. carotovorum.
The Rcs phosphorelay is a signal transduction system that influences the virulence phenotype of several pathogenic bacteria. In the plant pathogen Pectobacterium carotovorum subsp. carotovorum (Pcc)… Expand
Auxotrophy-based High Throughput Screening assay for the identification of Bacillus subtilis stringent response inhibitors
The stringent response is a central adaptation mechanism that allows bacteria to adjust their growth and metabolism according to environmental conditions. The functionality of the stringent response… Expand
Combination with antimicrobial peptide lyses improves loop-mediated isothermal amplification based method for Chlamydia trachomatis detection directly in urine sample
- Jekaterina Jevtuševskaja, Julia Uusna, +5 authors Ü. Langel
- Biology, Medicine
- BMC Infectious Diseases
- 13 July 2016
BackgroundChlamydia trachomatis is an obligate intracellular human pathogen and is the most common cause of sexually transmitted diseases affecting both men and women. The pathogen can cause… Expand
AepA of Pectobacterium is not involved in the regulation of extracellular plant cell wall degrading enzymes production
Plant cell wall degrading enzymes (PCWDE) are the major virulence determinants in phytopathogenic Pectobacterium, and their production is controlled by many regulatory factors. In this study, we… Expand
CLIP-Seq in Bacteria: Global Recognition Patterns of Bacterial RNA-Binding Proteins.
RNA-protein interactions are at the heart of many central cellular processes, and RNA-binding proteins (RBPs) associate with virtually all RNA molecules in a cell. In bacteria, global RBPs, often in… Expand