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The chloride content required for corrosion initiation of galvanized reinforcing bars is determined. The bars conform to ASTM A767, except that no chromate treatment was applied to allow the degree of hydrogen evolution for untreated bars to be evaluated. Test results, along with results for conventional (ASTM A615), low carbon chromium (ASTM A1035, MMFX),(More)
To investigate the expression of hypoxia inducible factor 1-alpha (HIF-1alpha) and its correlation with P53 and vascular endothelial growth factor (VEGF), immunohistochemical technique was employed to detect the protein expressions of HIF-1alpha, P53 and VEGF in specimens from 57 patients with lung cancer. The results indicated that the total positive(More)
To study the role and mechanisms of hypoxia-inducible factor-1alpha (HIF-1alpha) on the growth and tumorigenicity of lung cancer cells A549, the antisense oligonucleotide of HIF-1alpha was transfected to A549 cells. The effect of the antisense oligonucleotide on tumor growth in vitro and in vivo was evaluated by the growth rate suppression of A549 cells and(More)
The effect and mechanism of the ciglitazone on lung cancer cells A549 growth in vitro and in vivo were studied. Various concentrations of ciglitazone were added to the cultured A549 line, and the proliferation and differentiation of A549 cells were examined by MTT and cytometry analysis. A549 cells (1 x 10(6)/mouse) were inoculated subcutaneously into 20(More)
Lung alveolar epithelial cells are exposed to hypoxia under a variety of physiological and pathological conditions. It has been shown recently that miR-143, which can directly target the key glycolytic enzyme hexokinase II (HK2), may be regulated by miR-155. We investigated whether microRNAs contribute to the cellular glycolysis in response to hypoxia.(More)
BACKGROUND Angiogenesis is an important process required for tumor progression. Mucin 1 (MUC1) is a transmembrane glycoprotein that is aberrantly upregulated in many types of cancer, including non-small-cell lung cancer (NSCLC). However, the biological significance of MUC1 overexpression in lung cancer angiogenesis is not completely understood. METHODS We(More)
To study the expression of Angiopoietin 2 (Ang-2) gene and its relationship with clinical pathological characteristics of non-small cell lung cancer (NSCLC), expression of the Ang-2 mRNA was evaluated by employing reverse transcription polymerase chain reaction (RT-PCR) in cancerous tissues and paired adjacent noncancerous tissues from 52 patients. The(More)
No. 5 and No. 10 bars are tested for bond strength in accordance with ASTM A944. For each bar size, the bond strength of bars with deformations that exceed the maximum spacing requirements in ASTM A615 is compared with the bond strength of bars that meet the spacing requirements. All bars exceed the requirements for minimum deformation height. Research(More)
Galvanized reinforcement is evaluated to determine the chloride content required for corrosion initiation. The bars conform to ASTM A 767, except that no chromate treatment was applied. Specimens containing the galvanized bars are subjected to Southern Exposure test conditions that are terminated upon corrosion initiation, after which the chloride content(More)