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INTRODUCTION Heparin-binding protein (HBP) is an antimicrobial protein stored in neutrophil granules and plays a role in endothelial permeability regulation. The aim was to assess the diagnostic and prognostic value of measuring HBP in patients with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). METHODS Plasma HBP was collected from(More)
OBJECTIVES The aim was to assess the diagnostic and prognostic value of measuring pentraxin 3 (PTX3) together with C-reactive protein (CRP) in patients with ventilator-associated pneumonia (VAP). BACKGROUND The PTX3 values increase rapidly during multiple inflammatory conditions, but little is known about its characteristics in VAP. METHODS Measurement(More)
We compute the front speeds of the Kolmogorov-Petrovsky-Piskunov (KPP) re-active fronts in two prototypes of periodic incompressible flows (the cellular flows and the cat's eye flows). The computation is based on adaptive streamline diffusion methods for the advection-diffusion type principal eigenvalue problem associated with the KPP front speeds. In the(More)
The local renin-angiotensin system (RAS) is closely related to bone metabolism. However, it is unknown whether the local RAS is related to bone mineral density (BMD) in glucocorticoid-induced osteoporosis (GIOP). Here, we revealed that the two main characteristics of GIOP might inhibit bone formation and enhance bone resorption. The aim of this study is to(More)
We study the Kolmogorov-Petrovsky-Piskunov (KPP) minimal front speeds in spatially random shear flows in cylinders of various cross sections based on variational principle and an associated elliptic eigenvalue problem. We compare a standard finite element method and a two-scale finite element method in random front speed computations. The two-scale method(More)
Collagen type XI α1 (COL11A1), a minor fibrillar collagen, has been demonstrated to be involved in cell proliferation, migration and the tumorigenesis of many human malignancies. Previous studies have shown that COL11A1 may be a valuable diagnostic marker for non-small cell lung carcinoma (NSCLC). However, its biological function in NSCLC progression(More)
Based on some coupled discretizations, a local computational scheme is proposed and analyzed in this paper for a class of higher order finite element eigenvalue approximations. Its efficiency is proven by theoretical and numerical evidences. It is shown that the solution of an eigenvalue problem in a higher order finite element space may be reduced to the(More)
This paper presents our work on developing parallel computational methods for two-phase flow on modern parallel computers, where techniques for linear solvers and nonlinear methods are studied and the standard and inexact Newton methods are investigated. A multi-stage preconditioner for two-phase flow is applied and advanced matrix processing strategies are(More)