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INTRODUCTION Heparin-binding protein (HBP) is an antimicrobial protein stored in neutrophil granules and plays a role in endothelial permeability regulation. The aim was to assess the diagnostic and prognostic value of measuring HBP in patients with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). METHODS Plasma HBP was collected from(More)
OBJECTIVES The aim was to assess the diagnostic and prognostic value of measuring pentraxin 3 (PTX3) together with C-reactive protein (CRP) in patients with ventilator-associated pneumonia (VAP). BACKGROUND The PTX3 values increase rapidly during multiple inflammatory conditions, but little is known about its characteristics in VAP. METHODS Measurement(More)
Collagen type XI α1 (COL11A1), a minor fibrillar collagen, has been demonstrated to be involved in cell proliferation, migration and the tumorigenesis of many human malignancies. Previous studies have shown that COL11A1 may be a valuable diagnostic marker for non-small cell lung carcinoma (NSCLC). However, its biological function in NSCLC progression(More)
The local renin-angiotensin system (RAS) is closely related to bone metabolism. However, it is unknown whether the local RAS is related to bone mineral density (BMD) in glucocorticoid-induced osteoporosis (GIOP). Here, we revealed that the two main characteristics of GIOP might inhibit bone formation and enhance bone resorption. The aim of this study is to(More)
We compute the front speeds of the Kolmogorov-Petrovsky-Piskunov (KPP) reactive fronts in two prototypes of periodic incompressible flows (the cellular flows and the cat’s eye flows). The computation is based on adaptive streamline diffusion methods for the advection-diffusion type principal eigenvalue problem associated with the KPP front speeds. In the(More)
We study the Kolmogorov-Petrovsky-Piskunov (KPP) minimal front speeds in spatially random shear flows in cylinders of various cross sections based on variational principle and an associated elliptic eigenvalue problem. We compare a standard finite element method and a two-scale finite element method in random front speed computations. The two-scale method(More)
Based on some coupled discretizations, a local computational scheme is proposed and analyzed in this paper for a class of higher order finite element eigenvalue approximations. Its efficiency is proven by theoretical and numerical evidences. It is shown that the solution of an eigenvalue problem in a higher order finite element space may be reduced to the(More)
New reservoir simulators designed for parallel computers enable us to overcome performance limitations of personal computers and to simulate large-scale reservoir models. With development of parallel reservoir simulators, more complex physics and detailed models can be studied. The key to design efficient parallel reservoir simulators is not to improve the(More)