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The occurrence, distribution and bioaccumulation of 22 antibiotics, including eight fluoroquinolones (FQs), nine sulfonamides (SAs) and five macrolides (MLs), in the Haihe River were investigated. Surface water, sediment and fish samples were analyzed by HPLC-MS/MS. Ofloxacin, sulfamethoxazole, sulfadiazine, erythromycin and roxithromycin were found in all(More)
This study investigated the presence and distribution of 22 antibiotics, including eight quinolones, nine sulfonamides and five macrolides, in the water, sediments, and biota samples from Baiyangdian Lake, China. A total of 132 samples were collected in 2008 and 2010, and laboratory analyses revealed that antibiotics were widely distributed in the lake.(More)
In this study, we investigated the occurrences and fates of eight quinolones (QNs), nine sulfonamides (SAs), and five macrolides (MCs) in a wastewater reclamation plant (WRP) in Beijing, China. Among all the 22 antibiotics considered, quinolones were the dominant antibiotics in all samples (4916ngL(-1) in influents, 1869ngL(-1) in secondary effluents,(More)
Yield increases of cucumber following cover crops in a rotation system have been previously reported for intensive Chinese agricultural production. However, little information is available as to how this system affects soil microbial properties and nematodes. A 4-year field experiment on a greenhouse cucumber double-cropping system was conducted to(More)
OBJECTIVE To investigate daptomycin pharmacokinetics in critically ill patients receiving continuous venovenous hemodialysis to develop dosing recommendations. DESIGN Prospective, open-label pharmacokinetic study. SETTING : Intensive care units located within a teaching medical center. PATIENTS Eight adults with known/suspected Gram-positive(More)
The occurrence, removal efficiency and seasonal variation of 22 antibiotics, including eight fluoroquinolones, nine sulfonamides and five macrolides, were investigated in eight sewage treatment plants (STPs) in Beijing, China. A total of 14 antibiotics were detected in wastewater samples, with the maximum concentration being 3.1 μg L(-1) in the influent(More)
The occurrence and distribution of 14 organophosphate (OP) triesters and 5 diesters were investigated in sludge from eight sewage treatment plants (STPs) in Beijing, China, during 2008-2014. Tri(2-ethylhexyl) phosphate (TEHP) and tri-m-cresyl phosphate (TCrP) were the predominant triesters with the average concentration of 233-137 μg/kg, respectively. Also,(More)
The occurrence, spatial distribution and seasonal variation of 14 organophosphate esters (OPEs) were investigated in urban surface water (river and lake water) from July 2013 to June 2014 in Beijing, China. Sewage influent and effluent samples, as well as rainwater and road runoff samples were also analyzed as the potential sources of OPEs in surface water.(More)
Daptomycin is approved for the treatment of complicated skin and soft tissue infections, including diabetic wounds of the lower extremities, at a dose of 4 mg/kg of body weight once daily. For such localized tissue infections, drug concentrations in the interstitial space are an important determinant of successful therapy. In the diabetic population,(More)
The recycling of reclaimed wastewater for irrigation and road cleaning is an important strategy to minimize water scarcity in megacities. However, little is known regarding the potential accumulation of antibiotics contained in reclaimed wastewater in urban soil. We investigated the occurrence and distribution of eight quinolones (QNs), nine sulfonamides(More)