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The steady improvement in image/video editing techniques has enabled people to synthesize realistic images/videos conveniently. Some legal issues may occur when a doctored image cannot be distinguished from a real one by visual examination. Realizing that it might be impossible to develop a method that is universal for all kinds of images and JPEG is the(More)
MOTIVATION Since many important biological systems or processes are dynamic systems, it is important to study the gene expression patterns over time in a genomic scale in order to capture the dynamic behavior of gene expression. Microarray technologies have made it possible to measure the gene expression levels of essentially all the genes during a given(More)
BACKGROUND This study compared brain white matter integrity in two groups of patients with DSM-IV anxiety disorders. METHOD Seventeen patients with posttraumatic stress disorder (PTSD), 20 with generalized anxiety disorder (GAD), and 28 healthy controls were assessed on diffusion tensor imaging. RESULTS As compared to healthy controls, increased(More)
BACKGROUND One of the major challenges in currently chemotherapeutic theme is lacking effective biomarkers for drug response and sensitivity. Our current study focus on two promising biomarkers, ERCC1 (excision repair cross-complementing group 1) and BRCA1 (breast cancer susceptibility gene 1). To investigate their potential role in serving as biomarkers(More)
Latent Dirichlet allocation (LDA) is a popular topic modeling technique in academia but less so in industry, especially in large-scale applications involving search engine and online advertising systems. A main underlying reason is that the topic models used have been too small in scale to be useful; for example, some of the largest LDA models reported in(More)
In this study, resting state fMRI images and BOLD signals were recorded from 13 first-degree relatives of schizophrenic patients and 13 healthy controls. The data were analyzed with the ReHo approach after realignment, registration, and normalization in statistical parametric mapping 2 (SPM2). A two-sample t-test was used to analyze the ReHo differences(More)
Significant visual effects arise from surface mesostructure, such as fine-scale shadowing, occlusion and silhouettes. To efficiently render its detailed appearance, we introduce a technique called view-dependent displacement mapping (VDM) that models surface displacements along the viewing direction. Unlike traditional displacement mapping, VDM allows for(More)
Many studies have suggested that childhood maltreatment increase risk of adulthood major depressive disorder (MDD) and predict its unfavorable treatment outcome, yet the neural underpinnings associated with childhood maltreatment in MDD remain poorly understood. Here, we seek to investigate the whole-brain functional connectivity patterns in MDD patients(More)