Liesl J. Zuhlke

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IN HIS SHORT HISTORY OF ASTRONOMY (“ASTRONOMY’S GREATEST HITS,” NEWS FOCUS, 16 January, p. 326), T. Folger amply demonstrated Anglo-Saxon parochialism. Almost all major discoveries mentioned in his text are attributed to those from Britain or the United States. Why didn’t Folger name great scientists from other nations? He could have included a host of(More)
Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) remain major causes of heart failure, stroke and death among African women and children, despite being preventable and imminently treatable. From 21 to 22 February 2015, the Social Cluster of the Africa Union Commission (AUC) hosted a consultation with RHD experts convened by the Pan-African(More)
OBJECTIVE We examined whether the socio-economic circumstances of a developing country justify pulmonary artery banding (PAB) for the deferral of perceived high-risk patients requiring biventricular repair. METHODS A retrospective cohort analysis was done on 143 consecutive patients with ventricular anatomy suitable for a biventricular repair, who had a(More)
There is potential for the use of mobile phones to remotely identify patients with a high risk of heart conditions using automated auscultation. However, accurate heart sound analysis is dependent on the quality of heart sound recordings. This paper investigates the signal quality classification of phonocardiograms (PCGs) recorded on two devices (a 3M(More)
Methods For countries without high-quality vital registration data, we estimated prevalence and incidence with data from antenatal care clinics and population-based seroprevalence surveys, and with assumptions by age and sex on initial CD4 distribution at infection, CD4 progression rates (probability of progression from higher to lower CD4 cell-count(More)
The burden of illness associated with acquired cardiac disease in children in low-income and middle-income countries (LMIC) is significant and may be equivalent to that of congenital heart disease. Rheumatic heart disease, endomyocardial fibrosis, cardiomyopathy (including HIV cardiomyopathy) and tuberculosis are the most important causes. All are(More)
BACKGROUND Reported long-term outcome measures vary greatly between studies in Fontan patients making comprehensive appraisal of mortality hazard challenging. We sought to create a clinical risk score to assist monitoring of Fontan patients in the outpatient setting. METHODS A systematic review was conducted to evaluate risk factors for long-term (beyond(More)
Importance Comprehensive and timely monitoring of disease burden in all age groups, including children and adolescents, is essential for improving population health. Objective To quantify and describe levels and trends of mortality and nonfatal health outcomes among children and adolescents from 1990 to 2015 to provide a framework for policy discussion.(More)
BACKGROUND Despite an ageing Fontan population, data on late outcomes are still scarce. Reported outcome measures and determinants vary greatly between studies making comprehensive appraisal of mortality hazard challenging. METHODS We conducted a systematic review to evaluate causes and factors associated with late mortality in patients with Fontan(More)
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