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Prevalence and clinical association of gene mutations through multiplex mutation testing in patients with NSCLC: results from the ETOP Lungscape Project.

• Karen Kerr, Urania Dafni, +39 authors S. Peters
• Annals of oncology : official journal of the…
• 2018

Background Reported prevalence of driver gene mutations in non-small-cell lung cancer (NSCLC) is highly variable and clinical correlations are emerging. Using NSCLC biomaterial and clinical data from… (More)

Validation of a locked nucleic acid based wild-type blocking PCR for the detection of EGFR exon 18/19 mutations

• Liesbet Vliegen, Christophe A Dooms, Wim de Kelver, Eric V. Verbeken, Johan Vansteenkiste, Peter Vandenberghe
• Diagnostic pathology
• 2015

BACKGROUND Treatment decisions in advanced non-small cell lung cancer rely on accurate analysis of the EGFR mutation status in small tissue samples. Sanger sequencing of PCR products is unbiased and… (More)

Suitability of small bronchoscopic tumour specimens for lung cancer genotyping.

• Christophe A Dooms, Liesbet Vliegen, +8 authors Peter Vandenberghe
• Respiration; international review of thoracic…
• 2014

BACKGROUND Biomarker-driven clinical trials in advanced non-small cell lung cancer (NSCLC) usually accept biopsy specimens only, as cytology specimens are supposed to be more challenging due to low… (More)

Performance of standard procedures in detection of EGFR mutations in daily practice in advanced NSCLC patients selected according to the ESMO guideline: a large Caucasian cohort study

• Inge Hantson, Christophe A Dooms, +7 authors Johan Vansteenkiste
• Translational Respiratory Medicine
• 2014

ESMO consensus recommends EGFR mutation testing in never/former light smokers (<15 pack-years) or patients with non-squamous NSCLC. The aim of this work was to determine the frequency and clinical… (More)

The Influence of Elbow Flexion and Arm External Rotation on Peak Elbow Valgus Torque and Ball Velocity in Baseball Pitching

• Liesbet Vliegen
• 2018

Introduction Elbow injury, especially Ulnar Collateral Ligament (UCL) tear, is very common in baseball pitching. This is often attributed to high valgus torques repetitively stressing the ligament.… (More)

Cystic fibrosis transmembrane conductance regulator gene polymorphisms in patients with primary sclerosing cholangitis.

• Liesbet Henckaerts, M M J J R Jaspers, +8 authors Harry Cuppens
• Journal of hepatology
• 2009

BACKGROUND/AIMS Primary sclerosing cholangitis (PSC) is a progressive cholestatic disease commonly associated with inflammatory bowel disease (IBD) and characterized by fibrosing inflammatory… (More)

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