Learn More
Blind image deconvolution, i.e., estimating a blur kernel k and a latent image x from an input blurred image y, is a severely ill-posed problem. In this paper we introduce a new patch-based strategy for kernel estimation in blind de-convolution. Our approach estimates a " trusted " subset of x by imposing a patch prior specifically tailored towards modeling(More)
Most image restoration techniques build " universal " image priors, trained on a variety of scenes, which can guide the restoration of any image. But what if we have more specific training examples, e.g. sharp images of similar scenes? Surprisingly, state-of-the-art image priors don't seem to benefit from from context-specific training examples. Retraining(More)
Epithelial-mesenchymal transition (EMT) has been linked to cancer stem-like (CD44+) cell in the prostate cancer (PCa) metastasis. However, the molecular mechanism remains elusive. Here, we found EMT contributed to metastasis in PCa patients failed in androgen deprivation therapy (ADT). Castration TRAMP model also proved PCa treated with ADT promoted EMT(More)
To explore the necessity of maintenance, efficacy of low-dose and superiority of various combination therapies of Bacillus Calmette-Guérin (BCG) in treatment of superficial bladder cancer (BCa). Comprehensive searches of electronic databases (PubMed, Embase, and the Cochrane Library) were performed, then a systematic review and cumulative meta-analysis of(More)
BACKGROUND There is no consensus regarding whether androgen deprivation therapy (ADT) is associated with cardiovascular disease (CVD) and cardiovascular mortality (CVM). The objective of this study was to determine the role of ADT for prostate cancer (PCa) in development of cardiovascular events (CVD and CVM). METHODS AND FINDINGS We performed a(More)
BACKGROUND It is quite common that the genetic architecture of complex traits involves many genes and their interactions. Therefore, dealing with multiple unlinked genomic regions simultaneously is desirable. RESULTS In this paper we develop a regression-based approach to assess the interactions of haplotypes that belong to different unlinked regions, and(More)
In this document, we provide detailed mathematical derivations on the optimization procedures we have introduced in Sec. 4.1. in the paper. Specifically, we discuss the details on updating x and {σ i }. To facilitate our discussion, we start out with a simpler objective function below, which is based on the L 2 norm instead of using the Lorentzian penalty(More)
Custom optics is a necessity for many imaging applications. Unfortunately, custom lens design is costly (thousands to tens of thousands of dollars), time consuming (10-12 weeks typical lead time), and requires specialized optics design expertise. By using only inexpensive, off-the-shelf lens components the Lens Factory automatic design system greatly(More)
The aim of this study is to explore the oncological outcomes of hypofractionated radiotherapy for patients with prostate cancer. We systematically searched PubMed, Embase, and the Cochrane Library prior to April 2014 and references of relevant original papers and review articles. Unpublished data from meeting abstracts were supplemented. Studies comparing(More)
  • 1