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The FireGrid project aims to harness the potential of advanced forms of computation to support the response to large-scale emergencies (with an initial focus on the response to fires in the built environment). Computational models of physical phenomena are developed, and then deployed and computed on High Performance Computing resources to infer incident(More)
Glaucoma is a group of eye diseases that have common traits such as, high eye pressure, damage to the Optic Nerve Head and gradual vision loss. It affects peripheral vision and eventually leads to blindness if left untreated. The current common methods of pre-diagnosis of Glaucoma include measurement of Intra-Ocular Pressure (IOP) using Tonometer,(More)
(2007) Towards a grid-enabled simulation framework for nano-CMOS electronics. Abstract The electronics design industry is facing major challenges as transistors continue to decrease in size. The next generation of devices will be so small that the position of individual atoms will affect their behaviour. This will cause the transistors on a chip to have(More)
Modern scientific collaborations have opened up the opportunity of solving complex problems that involve multi-disciplinary expertise and large-scale computational experiments. These experiments usually involve large amounts of data that are located in distributed data repositories running various software systems, and managed by different organisations. A(More)
It is of high biomedical interest to identify gene interactions and networks that are associated with developmental and physiological functions in the mouse embryo. There are now large datasets with both spatial and ontological annotation of the spatio-temporal patterns of gene-expression that provide a powerful resource to discover potential mechanisms of(More)
Performance is an open issue in data intensive applications (e.g. data mining tasks). Parallel and distributed computing systems (e.g. multicore computing, grid computing, cloud computing,etc.), along with hybrid programming models (e.g. MapReduce, MPI, etc.), is seen a sought-after solution for accelerating data-intensive applications. One of main(More)
MOTIVATION Deciphering the regulatory and developmental mechanisms for multicellular organisms requires detailed knowledge of gene interactions and gene expressions. The availability of large datasets with both spatial and ontological annotation of the spatio-temporal patterns of gene expression in mouse embryo provides a powerful resource to discover the(More)
Identification and detection of dendritic spines in neuron images are of high interest in diagnosis and treatment of neurological and psychiatric disorders (e.g., Alzheimer's disease, Parkinson's diseases, and autism). In this paper, we have proposed a novel automatic approach using wavelet-based conditional symmetric analysis and regularized morphological(More)