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Modulation of Intestinal Epithelial Glycocalyx Development by Human Milk Oligosaccharides and Non‐Digestible Carbohydrates
Scope The epithelial glycocalyx development is of great importance for microbial colonization. Human milk oligosaccharides (hMOs) and non‐digestible carbohydrates (NDCs) may modulate glycocalyxExpand
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Human milk oligosaccharides and its acid hydrolysate LNT2 show immunomodulatory effects via TLRs in a dose and structure-dependent way
Abstract Human milk oligosaccharides (HMOs) have beneficial immune effects but the mechanisms of action are not well-understood. Here we study Toll-like receptor (TLR) signaling of the HMOs 2′-FL,Expand
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Human Milk Oligosaccharides Differently Modulate Goblet Cells Under Homeostatic, Proinflammatory Conditions and ER Stress
Scope Human milk oligosaccharides (hMOs) have beneficial effects on intestinal barrier function, but the mechanisms of action are not well understood. Here, the effects of hMOs on goblet cells, whichExpand
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More than sugar in the milk: human milk oligosaccharides as essential bioactive molecules in breast milk and current insight in beneficial effects.
Human milk is the gold standard for newborn infants. Breast milk not only provides nutrients, it also contains bioactive components that guide the development of the infant's intestinal immuneExpand
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Human Milk Oligosaccharides Mediate the Crosstalk Between Intestinal Epithelial Caco-2 Cells and Lactobacillus PlantarumWCFS1in an In Vitro Model with Intestinal Peristaltic Shear Force
ABSTRACT Background The intestinal epithelial cells, food molecules, and gut microbiota are continuously exposed to intestinal peristaltic shear force. Shear force may impact the crosstalk of humanExpand
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Lactic acid bacteria secrete toll like receptor 2 stimulating and macrophage immunomodulating bioactive factors
Abstract Lactic acid bacteria (LAB) can support host health and crosstalks between ligands on bacterial cells and Toll-like receptors (TLR) are known as key inducers of these health effects.Expand
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Nonlinear optical effects in optical trapping with femtosecond laser
A phenomenon called “trap split” was found when gold nanoparticles were trapped by linear polarized femtosecond laser pulses. The trap split was strongly dependent on the polarization of trappingExpand
Mom's sweet gift: The beneficial effects of human milk oligosaccharides and their structure-function relationships
Human milk oligosaccharide (hMO) is the third-largest solid compound and the most abundant bioactive molecule in human milk. The beneficial effects of hMOs in human milk are broadly acknowledged butExpand
Two-Photon Luminescence and Second Harmonic Generation from Gold Micro-Plates
TLDR
We investigated the TPL and SHG of micron-sized gold plates excited by a wavelength tunable femtosecond laser with a two-photon fluorescence microscope, and found the dependence on wavelength, power and polarization of the excitation light. Expand
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