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Inhalation of glycopyrronium inhibits cigarette smoke-induced acute lung inflammation in a murine model of COPD.
- Liang-liang Shen, Ya-nan Liu, +7 authors Q. Xie
- International immunopharmacology
- 1 February 2014
Glycopyrronium bromide (GB) is a muscarinic receptor antagonist that has been used as a long-acting bronchodilator in chronic obstructive pulmonary disease (COPD) patients. The aim of this study was… Expand
Simvastatin delivery via inhalation attenuates airway inflammation in a murine model of asthma.
The dose-response of the pleiotropic effects of statins on airway inflammation has not yet been established and may differ from that of their cholesterol-lowering effects. High oral doses of statins… Expand
Apple polyphenol protects against cigarette smoke-induced acute lung injury.
OBJECTIVE Chronic obstructive pulmonary disease (COPD) is a complex chronic inflammatory disease involving oxidative stress as well as a wide variety of cells activated from smoking cigarettes. There… Expand
c-Myc Overexpression Promotes Oral Cancer Cell Proliferation and Migration by Enhancing Glutaminase and Glutamine Synthetase Activity.
- T. Wang, B. Cai, Mingchao Ding, Zhong-ping Su, Y. Liu, Liang-liang Shen
- The American journal of the medical sciences
- 1 September 2019
BACKGROUND This study aimed to investigate whether glutaminase (GLS) and glutamine synthetase (GS) are involved in c-Myc-mediated tumor development in oral cancer. METHODS The correlation between… Expand